(Q58134938)

English

Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530

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scholarly article

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Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530 (English)

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breast neoplasm

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Heung-Chin Cheng

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Heung-Chin Cheng

4

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author name string

Cay Egan

1

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Andrew Pang

2

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Denise Durda

3

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Jerry H Wang

5

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Donald J Fujita

6

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language of work or name

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publication date

February 1999

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18

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1227-1237

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5

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202233

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Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

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pp60c-src activation in human colon carcinoma

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Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

1 reference

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1002 protein phosphatases?

1 reference

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CDC25 phosphatases as potential human oncogenes

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

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Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells

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Involvement of pp60c-src with two major signaling pathways in human breast cancer

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

1 reference

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

1 reference

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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

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Functional interaction between the epidermal growth factor receptor and c-Src kinase activity

1 reference

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

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A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

1 reference

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

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Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

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Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene

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pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

1 reference

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Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

1 reference

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Characterization of two activated mutants of human pp60c-src that escape c-Src kinase regulation by distinct mechanisms

1 reference

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based on heuristic

inferred from DOI database lookup

Protein-tyrosine phosphatase epsilon. An isoform specifically expressed in mouse mammary tumors initiated by v-Ha-ras OR neu.

1 reference

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based on heuristic

inferred from DOI database lookup

Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice

1 reference

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based on heuristic

inferred from DOI database lookup

Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region

1 reference

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based on heuristic

inferred from DOI database lookup

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

1 reference

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based on heuristic

inferred from DOI database lookup

The receptor-like protein tyrosine phosphatase alpha: a role in cell proliferation and oncogenesis

1 reference

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based on heuristic

inferred from DOI database lookup

Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase

1 reference

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based on heuristic

inferred from DOI database lookup

Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

1 reference

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based on heuristic

inferred from DOI database lookup

Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C

1 reference

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based on heuristic

inferred from DOI database lookup

Physical and functional interactions between Lyn and p34cdc2 kinases in irradiated human B-cell precursors

1 reference

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based on heuristic

inferred from DOI database lookup

1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1202233

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