(Q39780156)

English

Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder

scientific article published on March 1997

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

9

object named as

A Atala

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Europe PubMed Central

PMC publication ID

14 September 2017

author name string

M R Freeman

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

J J Yoo

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

G Raab

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

S Soker

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

R M Adam

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

F X Schneck

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

A A Renshaw

7

1 reference

Europe PubMed Central

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14 September 2017

M Klagsbrun

8

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

1 March 1997

1 reference

Europe PubMed Central

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14 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

99

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

1028-1036

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: differential production and release by CD4+ and CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Significance of epidermal growth factor receptor and c-erbB-2 protein expression in transitional cell cancer of the upper urinary tract for tumour recurrence at the urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Induction of heparin-binding EGF-like growth factor expression during myogenesis. Activation of the gene by MyoD and localization of the transmembrane form of the protein on the myotube surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: a potential pathologic role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Identification of a mucin layer in the urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Phenotypic and cytogenetic characterization of human bladder urothelia expanded in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Cell replacement and differentiation in transitional epithelium: a histological and autoradiographic study of the guinea-pig bladder and ureter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Isolation and characterization of a macrophage-derived heparin-binding growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

22 September 2017

Urinary neutrophil chemotactic factors in interstitial cystitis patients and a rabbit model of bladder inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

25 September 2017

Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

25 September 2017

The heparin-binding domain of heparin-binding EGF-like growth factor can target Pseudomonas exotoxin to kill cells exclusively through heparan sulfate proteoglycans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

25 September 2017

The human urinary epidermal growth factor (EGF) precursor. Isolation of a biologically active 160-kilodalton heparin-binding pro-EGF with a truncated carboxyl terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

25 September 2017

Eosinophils expressing heparin-binding EGF-like growth factor mRNA localize around lung microvessels in pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Culture of a prostatic cell line in basement membrane gels results in an enhancement of malignant properties and constitutive alterations in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Lymphocyte sub-populations in the bladder wall in normal bladder, bacterial cystitis and interstitial cystitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Prognostic value of epidermal growth factor-receptor, T138 and T43 expression in bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Effects of urine and continued exposure to carcinogen on progression of early neoplastic urinary bladder lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Presence of heparin binding growth factor in mouse bladder tumors and urine from mice with bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Epidermal growth factor--interactions with normal and malignant urothelium: in vivo and in situ studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Increased levels of fibroblast growth factor-like activity in urine from patients with bladder or kidney cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Identification of epidermal growth factor as a component of the rat urinary bladder tumor-enhancing urinary fractions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Stimulation of stromal cell growth by normal rat urothelial cell-derived epidermal growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

15 June 2018

Transferrin as a growth factor for rat bladder carcinoma cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

17 June 2018

Tumor-promoting effect of urinary epidermal growth factor in rat urinary bladder carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

17 June 2018

Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

20 August 2018

Epidermal-growth-factor-receptor expression is associated with rapid tumor proliferation in bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

20 August 2018

Biosynthesis and processing by phorbol ester of the cells surface-associated precursor form of heparin-binding EGF-like growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

20 August 2018

Enhancement by urine of urinary bladder carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

20 August 2018

The effect of normal rat urine on mucosal regeneration in heterotopic urinary bladder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507911

20 August 2018

Growth of normal and neoplastic urothelium and response to epidermal growth factor in a defined serum-free medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and malignant human urothelium: in vitro effects of epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor in the normal and neoplastic kidney and bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the diphtheria toxin receptor-binding domain to the carboxyl-terminal Mr approximately 6000 region of the toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of urine on clonal growth of human bladder cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased immunodetection of acidic fibroblast growth factor in bladder cancer, detectable in urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epidermal growth factor receptor in invasive transitional cell carcinoma of the urinary bladder. A multivariate survival analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for the function of glycosaminoglycans in the urinary tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term outcome related to epidermal growth factor receptor status in bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin-like molecules on the cell surface potentiate binding of diphtheria toxin to the diphtheria toxin receptor/membrane-anchored heparin-binding epidermal growth factor-like growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced tumorigenesis of NR6 cells which express non-down-regulating epidermal growth factor receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9062361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119230

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

release_ntby5gsw4rgb7jqbhc3rp6wnhm

1 reference

https://api.fatcat.wiki/v0/release/ntby5gsw4rgb7jqbhc3rp6wnhm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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