(Q39793519)

14 September 2017

title

Antitumor activity and toxicity of anti-HER2 immunoRNase scFv 4D5-dibarnase in mice bearing human breast cancer xenografts (English)

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14 September 2017

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6

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14 September 2017

Taras G Balandin

1

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14 September 2017

Evelina Edelweiss

2

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14 September 2017

Natalia V Andronova

3

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14 September 2017

Elena M Treshalina

4

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14 September 2017

Alexander M Sapozhnikov

5

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14 September 2017

publication date

30 September 2009

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Investigational New Drugs

14 September 2017

published in

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14 September 2017

volume

29

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14 September 2017

issue

1

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14 September 2017

page(s)

22-32

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A general method for isolation of high molecular weight DNA from eukaryotes

14 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS10637-009-9329-2

Antibody-targeted RNase fusion proteins (immunoRNases) for cancer therapy

21 January 2018

1 reference

12 December 2020

Role of exon-16-deleted HER2 in breast carcinomas

1 reference

12 December 2020

Immnochemical Properties of Ribonuclease T1 in Relation to Other Ribonucleases*

1 reference

12 December 2020

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

1 reference

12 December 2020

Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line.

1 reference

12 December 2020

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

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12 December 2020

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

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12 December 2020

Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues

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12 December 2020

Intracellular route and mechanism of action of ERB-hRNase, a human anti-ErbB2 anticancer immunoagent

1 reference

12 December 2020

A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas.

1 reference

12 December 2020

The ErbB signaling network: receptor heterodimerization in development and cancer

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12 December 2020

Barnase as a new therapeutic agent triggering apoptosis in human cancer cells

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12 December 2020

Overexpression of HER-2 in ovarian carcinomas

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12 December 2020

Fluorescent immunolabeling of cancer cells by quantum dots and antibody scFv fragment

1 reference

12 December 2020

Improving in vivo folding and stability of a single-chain Fv antibody fragment by loop grafting

1 reference

12 December 2020

Nephrotoxic effects of bacterial ribonucleases in the isolated perfused rat kidney

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12 December 2020

Visualization of cancer cells by means of the fluorescent EGFP-barnase protein

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12 December 2020

A new vector for controllable expression of an anti-HER2/neu mini-antibody-barnase fusion protein in HEK 293T cells

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12 December 2020

Relevance of breast cancer cell lines as models for breast tumours: an update

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12 December 2020

Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell lines

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12 December 2020

Binase induces apoptosis of transformed myeloid cells and does not induce T-cell immune response

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12 December 2020

Expression of single-chain antibody-barstar fusion in plants.

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

Engineered turns of a recombinant antibody improve its in vivo folding

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12 December 2020

Binase and other microbial RNases as potential anticancer agents

1 reference

12 December 2020

A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity.

1 reference

12 December 2020

Tumor targeting of mono-, di-, and tetravalent anti-p185(HER-2) miniantibodies multimerized by self-associating peptides

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12 December 2020

Phase II trial of trastuzumab followed by weekly paclitaxel/carboplatin as first-line treatment for patients with metastatic breast cancer

1 reference

12 December 2020

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

1 reference

12 December 2020

Targeting cancer cells by using an antireceptor antibody-photosensitizer fusion protein

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12 December 2020

From immunotoxins to immunoRNases

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12 December 2020

Design of multivalent complexes using the barnase*barstar module.

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12 December 2020

Protein-protein interaction: a genetic selection for compensating mutations at the barnase-barstar interface

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12 December 2020

PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting

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12 December 2020

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12 December 2020

10.1007/S10637-009-9329-2

Identifiers

DOI

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14 September 2017

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