(Q39801202)

English

Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection.

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7 February 2020

Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection (English)

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7 February 2020

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7 February 2020

Richard Harrison

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7 February 2020

Daniela Delneri

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7 February 2020

Milena Romanello

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Milena Romanello

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7 February 2020

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Nicoletta Bivi

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7 February 2020

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Ian Clarke

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7 February 2020

David C Hoyle

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7 February 2020

Luigi Moro

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7 February 2020

Fulvia Ortolani

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7 February 2020

Antonella Bonetti

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7 February 2020

Franco Quadrifoglio

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7 February 2020

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10 September 2009

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7 February 2020

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7 February 2020

10

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7 February 2020

9

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7 February 2020

R93

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7 February 2020

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11 June 2022

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

https://scigraph.springernature.com/pub.10.1186/gb-2009-10-9-r93

0 references

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells.

1 reference

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22 September 2017

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

1 reference

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22 September 2017

Cellular processes and pathways that protect Saccharomyces cerevisiae cells against the plasma membrane-perturbing compound chitosan

1 reference

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22 September 2017

Acquired resistance to bisphosphonates in Paget's disease of bone.

1 reference

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22 September 2017

Breast cancer: bisphosphonate therapy for metastatic bone disease

1 reference

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22 September 2017

Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status

1 reference

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22 September 2017

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

1 reference

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22 September 2017

Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis

1 reference

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22 September 2017

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

1 reference

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22 September 2017

Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity

1 reference

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22 September 2017

Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast

1 reference

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22 September 2017

Characterization of synthetic DNA bar codes in Saccharomyces cerevisiae gene-deletion strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

GoMiner: a resource for biological interpretation of genomic and proteomic data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Antitumor effects of bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

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22 September 2017

Systematic screen for human disease genes in yeast

1 reference

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22 September 2017

Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Cell cycle regulation of DNA replication initiator factor Dbf4p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

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22 September 2017

Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro.

1 reference

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22 September 2017

Bisphosphonates: mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Mutants of yeast defective in iso-1-cytochrome c.

1 reference

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More powerful procedures for multiple significance testing

1 reference

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22 September 2017

Purification and complete sequence of a small proteolipid associated with the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

22 September 2017

Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

25 September 2017

Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

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Genomic profiling of drug sensitivities via induced haploinsufficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

17 June 2018

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

17 June 2018

Human genetic diseases: a cross-talk between man and yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

17 June 2018

Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures.

1 reference

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20 August 2018

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1 reference

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Cdc7 is an active kinase in human cancer cells undergoing replication stress.

1 reference

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Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.

1 reference

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20 August 2018

Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

20 August 2018

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768982

20 August 2018

Quantitative analysis of yeast gene function using competition experiments in continuous culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19744312

12 December 2020

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10.1186/GB-2009-10-9-R93

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7 February 2020

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7 February 2020

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7 February 2020

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