(Q39804200)

14 September 2017

title

Plasma membrane nanoswitches generate high-fidelity Ras signal transduction (English)

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14 September 2017

5

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14 September 2017

Tianhai Tian

1

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14 September 2017

Angus Harding

2

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14 September 2017

Kerry Inder

3

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14 September 2017

Sarah Plowman

4

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14 September 2017

John F Hancock

6

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14 September 2017

publication date

8 July 2007

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14 September 2017

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14 September 2017

volume

9

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14 September 2017

issue

8

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14 September 2017

page(s)

905-914

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https://scigraph.springernature.com/pub.10.1038/ncb1615

14 September 2017

exact match

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cites work

Single-molecule imaging analysis of Ras activation in living cells

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H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton

21 January 2018

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Direct visualization of Ras proteins in spatially distinct cell surface microdomains

21 January 2018

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Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells

21 January 2018

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Lipid rafts: contentious only from simplistic standpoints

21 January 2018

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Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane Molecules

21 January 2018

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Model systems, lipid rafts, and cell membranes

21 January 2018

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The RAF proteins take centre stage

21 January 2018

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Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells.

21 January 2018

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SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

21 January 2018

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Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

21 January 2018

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Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

21 January 2018

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Ultrasensitivity in the mitogen-activated protein kinase cascade

21 January 2018

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Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase

21 January 2018

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The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

21 January 2018

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Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

21 January 2018

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MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network

21 January 2018

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Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

21 January 2018

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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

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Regulation of Raf-1 by direct feedback phosphorylation.

21 January 2018

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Subcellular localization determines MAP kinase signal output.

21 January 2018

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Nanoscale organization of multiple GPI-anchored proteins in living cell membranes.

21 January 2018

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Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

21 January 2018

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H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

21 January 2018

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

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H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis

21 January 2018

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Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways

21 January 2018

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Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

21 January 2018

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How robust are switches in intracellular signaling cascades?

21 January 2018

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Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

21 January 2018

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Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible

21 January 2018

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Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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The state of lipid rafts: from model membranes to cells

21 January 2018

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Identification of residues and domains of Raf important for function in vivo and in vitro

21 January 2018

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Electron microscopic imaging of Ras signaling domains

21 January 2018

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Graphical representation and multicomponent analysis of single-frequency fluorescence lifetime imaging microscopy data.

21 January 2018

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Fluorescence lifetime heterogeneity resolution in the frequency domain by lifetime moments analysis

21 January 2018

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Evaluation of global analysis algorithms for single frequency fluorescence lifetime imaging microscopy data

21 January 2018

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Ras plasma membrane signalling platforms

21 January 2018

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7 January 2021

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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7 January 2021

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

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7 January 2021

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

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7 January 2021

Identifiers

DOI

10.1038/NCB1615

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release_wrzjrgufazc2tjbqzmqpjky4tq

14 September 2017

Fatcat ID

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