(Q39806153)

English

The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

1 reference

based on heuristic

inferred from title

author name string

Roshini M Ponnamperuma

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Kathryn E King

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Tamador Elsir

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Adam B Glick

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Geoffrey M Wahl

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Monica Nister

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Wendy C Weinberg

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

publication date

1 October 2009

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

219

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

263-274

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Adenovirus p53 gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Duel nature of TGF-beta signaling: tumor suppressor vs. tumor promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

p53's double life: transactivation-independent repression of homologous recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Restoring p53-dependent tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

TP53: a key gene in human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

The p53 proto-oncogene can act as a suppressor of transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

22 September 2017

Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

25 September 2017

Loss of p21CIP1/WAF1 does not recapitulate accelerated malignant conversion caused by p53 loss in experimental skin carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

15 June 2018

p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

15 June 2018

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

15 June 2018

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

15 June 2018

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

15 June 2018

Explaining the biological activity of transactivation-deficient p53 variants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

p53 must be competent for transcriptional regulation to suppress tumor formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

p53 gene dosage modifies growth and malignant progression of keratinocytes expressing the v-rasHa oncogene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208754

20 August 2018

Characterization of the molecular mechanisms for p53-mediated differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of DNA binding and transactivation in p53 by nuclear localization and phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation of p53 loss of function and v-Ha-ras in transformation of mouse keratinocyte cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19718706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PATH.2600

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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