(Q39807622)

14 September 2017

Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells (English)

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14 September 2017

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H Iha

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author name string

H Hasegawa

1

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14 September 2017

Y Yamada

2

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14 September 2017

K Tsukasaki

4

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14 September 2017

K Nagai

5

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14 September 2017

S Atogami

6

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14 September 2017

K Sugahara

7

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14 September 2017

K Tsuruda

8

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14 September 2017

A Ishizaki

9

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14 September 2017

S Kamihira

10

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14 September 2017

27 August 2009

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14 September 2017

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14 September 2017

23

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14 September 2017

2090-2101

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14 September 2017

11

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https://scigraph.springernature.com/pub.10.1038/leu.2009.171

14 September 2017

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The current status of therapy for adult T-cell leukaemia-lymphoma in Japan

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Shaping genetic alterations in human cancer: the p53 mutation paradigm

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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MDM2 inhibitors for cancer therapy

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

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A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 product

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Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines

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p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

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Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera, abrogates TRAIL resistance in leukemia cells

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21 January 2018

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Tumour biology: senescence in premalignant tumours

21 January 2018

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Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

21 January 2018

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Inhibition of methyltransferases results in induction of g2/m checkpoint and programmed cell death in human T-lymphotropic virus type 1-transformed cells

21 January 2018

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PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells

21 January 2018

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Small-molecule inhibitor which reactivates p53 in human T-cell leukemia virus type 1-transformed cells

21 January 2018

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Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence

21 January 2018

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Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

21 January 2018

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The clinical trail of TRAIL.

21 January 2018

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TRAIL: a multifunctional cytokine

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p16 and ARF: activation of teenage proteins in old age.

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Impact of p53 aberration on the progression of Adult T-cell Leukemia/Lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.171

inferred from DOI database lookup

7 January 2021

based on heuristic

Adult T-cell leukemia: structures and expression of the p53 gene

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.171

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2009.171

1 reference

14 September 2017

1 reference