(Q39831942)

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Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes (English)

1 reference

Europe PubMed Central

15 September 2017

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Cliona M Rooney

7

object named as

Cliona M Rooney

1 reference

Europe PubMed Central

15 September 2017

4

object named as

Ann M Leen

1 reference

Europe PubMed Central

15 September 2017

author name string

Anjum S Kaka

1

1 reference

Europe PubMed Central

15 September 2017

Donald R Shaffer

2

1 reference

Europe PubMed Central

15 September 2017

Ryan Hartmaier

3

1 reference

Europe PubMed Central

15 September 2017

An Lu

5

1 reference

Europe PubMed Central

15 September 2017

Adham Bear

6

1 reference

Europe PubMed Central

15 September 2017

Aaron E Foster

8

1 reference

Europe PubMed Central

15 September 2017

publication date

1 September 2009

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Europe PubMed Central

15 September 2017

Journal of Immunotherapy

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Europe PubMed Central

15 September 2017

32

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Europe PubMed Central

15 September 2017

726-736

1 reference

Europe PubMed Central

15 September 2017

7

1 reference

Europe PubMed Central

15 September 2017

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

1 reference

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Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients

1 reference

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Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment

1 reference

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

1 reference

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1 reference

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Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy

1 reference

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

1 reference

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Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer

1 reference

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Autologous designer antigen-presenting cells by gene modification of T lymphocyte blasts with IL-7 and IL-12.

1 reference

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IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

1 reference

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Cancer regression in patients after transfer of genetically engineered lymphocytes

1 reference

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

1 reference

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Expression of RHAMM/CD168 and other tumor-associated antigens in patients with B-cell chronic lymphocytic leukemia.

1 reference

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Adoptive immunotherapy for cancer: building on success

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Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.

1 reference

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IL-21 influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

1 reference

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A new dynamic model of CD8+ T effector cell responses via CD4+ T helper-antigen-presenting cells

1 reference

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

1 reference

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Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression

1 reference

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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CD27 expression promotes long-term survival of functional effector-memory CD8+ cytotoxic T lymphocytes in HIV-infected patients

1 reference

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Biology of IL-21 and the IL-21 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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T-cell receptor/CD28 engagement when combined with prostaglandin E2 treatment leads to potent activation of human T-cell leukemia virus type 1.

1 reference

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Interleukin-21 inhibits dendritic cell activation and maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790367

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

1 reference

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1 reference

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

1 reference

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1 reference

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A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

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Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

1 reference

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Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

1 reference

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1 reference

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

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1 reference

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1 reference

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1 reference

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

1 reference

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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

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Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19561536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19561536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19561536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/CJI.0B013E3181AD4071

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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