(Q39833070)

15 September 2017

Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro (English)

1 reference

15 September 2017

Plasmodium falciparum

0 references

5-fluoroorotic acid

1 reference

ChEBI release 2020-05-28

1

Rathod PK

1 reference

15 September 2017

Khatri A

2

1 reference

15 September 2017

Hubbert T

series ordinal

3

1 reference

15 September 2017

Milhous WK

series ordinal

4

1 reference

15 September 2017

language of work or name

English

0 references

publication date

1 July 1989

1 reference

Antimicrobial Agents and Chemotherapy

15 September 2017

1 reference

15 September 2017

33

1 reference

15 September 2017

7

1 reference

15 September 2017

1090-1094

1 reference

Spread of chloroquine resistance in Plasmodium falciparum

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Pyrimidine Nucleotide Biosynthesis in Animals: Genes, Enzymes, and Regulation of UMP Biosynthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Characterization of a newly derived human sarcoma cell line (HT-1080).

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Human malaria parasites in continuous culture

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Conversion of dihydroorotate to orotate in parasitic protozoa

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Membrane Transport of Purine and Pyrimidine Bases and Nucleosides in Animal Cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Metabolism of 5-fluorouracil in cultured cells. Protection from 5-fluorouracil cytotoxicity by purines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Biochemistry of Plasmodium (malarial parasites)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

In vitro antimalarial activity of nucleic acid precursor analogues in the simian malaria Plasmodium knowlesi

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Antitumor activity of DL-threo-beta-fluoroasparagine against human leukemia cells in culture and L1210 cells in DBA mice.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Purine and Pyrimidine Synthesis by the Avian Malaria Parasite, Plasmodium lophurae*

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

In vitro inhibition of Plasmodium falciparum by pyrazofurin, an inhibitor of pyrimidine biosynthesis de novo

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Purification of the bifunctional thymidylate synthase-dihydrofolate reductase complex from the human malaria parasite Plasmodium falciparum

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Characterization of a new human diploid cell strain, IMR-90.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Culture of human malaria parasites Plasmodium falciparum

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Studies on fluorinated pyrimidines. V. Effects on nucleic acid metabolism in vitro.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Orotidylate-metabolizing enzymes of the human malarial parasite, Plasmodium falciparum, differ from host cell enzymes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Dihydroorotic acid dehydrogenase: introduction into erythrocyte by the malaria parasite

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Nucleic acid metabolism in experimental malaria. 1. Studies on the incorporation of thymidine, uridine, and adenosine in the malaria parasite (Plasmodium berghei and Plasmodium vinckei)

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Pyrimidine de novo synthesis during the life cycle of the intraerythrocytic stage of Plasmodium falciparum

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Incorporation of Radioactive Precursors into DNA and RNA of Plasmodium knowlesi in vitro

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=176067

Biochemical strategy of the genome as expressed in regulation of pyrimidine metabolism

20 August 2018

1 reference

12 December 2020

Salvage of circulating pyrimidine nucleosides by tissues of the mouse

1 reference

12 December 2020

The source of purines and pyrimidines in Plasmodium berghei

1 reference

12 December 2020

The synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. I. Some properties of the enzyme from P1534J mouse leukemic cells

1 reference

12 December 2020

A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa

1 reference

12 December 2020

Pyrimidine biosynthesis in Plasmodium berghei

1 reference

12 December 2020

High-dose 5-fluorouracil with delayed uridine "rescue" in mice

1 reference

12 December 2020

Plasmodium falciparum: cloning by single-erythrocyte micromanipulation and heterogeneity in vitro

1 reference

12 December 2020

The enzymatic synthesis of 5-fluorouridine 5'-phosphate

1 reference

12 December 2020

Dihydroorotate dehydrogenase, orotate phosphoribosyltransferase and orotidine-5′-phosphate decarboxylase in Plasmodium falciparum

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.33.7.1090

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

2675756

1 reference