(Q39834940)

15 September 2017

1 reference

19 November 2019

Partitioning and lipophilicity in quantitative structure-activity relationships (English)

1 reference

15 September 2017

1 reference

19 November 2019

J C Dearden

1

1 reference

15 September 2017

1 September 1985

2 references

Environmental Health Perspectives

15 September 2017

19 November 2019

2 references

15 September 2017

19 November 2019

61

1 reference

15 September 2017

203-228

1 reference

Principles and practice of Hansch analysis: a guide to structure-activity correlation for the medicinal chemist

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Lipophilic Character and Biological Activity of Drugs II: The Parabolic Case

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Linear Relationships between Lipophilic Character and Biological Activity of Drugs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatography

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Physicochemical-activity relations in practice. 1. Rational and self-consistent data bank

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Lipophilicity and drug activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Lipophilicity and biological acitivity. Drug transport and drug distribution in model systems and in biological systems

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Use of A Physical Multi-Cell Model to Confirm Theoretical Predictions of Biphasic Structure-Activity Relationships

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Effect of Lipophilicity of Ionisable Drugs on Deviations from Expected Ph-Partition Behaviour

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Quantitative Structure-Activity Study of Inhibition of Blood Platelet Aggregation by Aspirin Derivatives

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Quantitative structure-analgesic activity studies of some alkyl derivatives of paracetamol (4-hydroxyacetanilide [proceeding]

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Proceedings: Steric enhancement of resonance: an explanation of the anomalously high partition coefficients of some phenoxyacetic acids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Proceedings: Ortho-effects in structure-activity studies; correlation of pie values of o- and p-substituents in acetanilide

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Conformation Partition and Drug Design

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

A new form of chromatogram employing two liquid phases: A theory of chromatography. 2. Application to the micro-determination of the higher monoamino-acids in proteins

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Intestinal absorption-partition relationships: A tentative functional nonlinear model

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Molecular connectivity: a novel method for prediction of bioconcentration factor of hazardous chemicals.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Molecular weight and therapeutic dose of drug

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Solubility and partitioning VI: octanol solubility and octanol-water partition coefficients.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

The use of substituent constants in drug modification

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

The linear free-energy relationship between partition coefficients and the binding and conformational perturbation of macromolecules by small organic compounds.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

The membrane concentrations of alcohol anesthetics

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Parabolic relation between drug potency and hydrophobicity

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Structure-activity correlations of morphinelike analgetics based on efficiencies following intravenous and intraventricular application

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Structure of medicinal chemistry

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Relationships between the biological and physicochemical properties of series of compounds

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Calculation of hydrophobic constant (log P) from .pi. and f constants

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Quantitative structure-activity relationships. IV. Non-linear dependence of biological activity on hydrophobic character: a new model

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Theoretical model-based equations for the linear free energy relationships of the biological activity of ionizable substances. 1. Equilibrium-controlled potency

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Hydrogen-bonding parameter and its significance in quantitative structure--activity studies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Simple procedure for determining octanol--aqueous partition, distribution, and ionization coefficients by reversed-phase high-pressure liquid chromatography

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

A MATHEMATICAL CONTRIBUTION TO STRUCTURE-ACTIVITY STUDIES.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Solubility and partitioning I: Solubility of nonelectrolytes in water.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Lipophilicity, molecular weight, and drug action: reexamination of parabolic and bilinear models

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Passive permeation of organic compounds through biological tissue: a non-steady-state theory

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

An analysis of the structure-activity relationship in the adrenergic blocking activity of the beta-haloalkylamines

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568760

Enthalpies of solution of a series of m-alkoxy phenols in water, n-octanol and water-n-octanol mutually saturated: derivation of the thermodynamic parameters for solute transfer between these solvents

20 August 2018

1 reference

12 December 2020

Liquid-liquid partition coefficients by high-pressure liquid chromatography

1 reference

12 December 2020

Analysis and prediction of partition coefficients of meta- and para-disubstituted benzenes in terms of substituent effects

1 reference

12 December 2020

Determination of octanol-water equivalent partition coefficients of indolizine and substituted 2-phenylindolizines by reversed-phase high-pressure liquid chromatography and fragmentation values

1 reference

12 December 2020

Buccal absorption as a parameter of analgesic activity of some p-substituted acetanilides

1 reference

12 December 2020

Chance correlations in structure-activity studies using multiple regression analysis

1 reference

12 December 2020

1 reference

12 December 2020

Effects of different buffer species on partition coefficients of drugs used in quantitative structure-activity relationships

1 reference

12 December 2020

Quantitative structure-activity relationships: the Van't Hoff heats of transfer of resorcinol monoethers from water to n-octanol

1 reference

12 December 2020

Application of SCAP to drug design. 1. Prediction of octanol-water partition coefficients using solvent-dependent conformational analyses

1 reference

12 December 2020

Homologous series of hydrophobic compounds in the equilibrium between an aqueous and hydrophobic phase. II. Biological activity and hydrophobic interactions with the receptor

1 reference

12 December 2020

Determination of thermodynamics of the methylene group in solutions of drug molecules

1 reference

12 December 2020

Effect of the solvent-dependent conformational system of hydroxyureas on predicted vs. observed log P

1 reference

12 December 2020

Molecular Connectivity III: Relationship to Partition Coefficients

1 reference

12 December 2020

Molecular topology and narcosis. A quantitative structure-activity relationship (QSAR) study of alcohols using complementary information content (CIC)

1 reference

12 December 2020

RM values of xanthone derivatives in structure-activity studies

1 reference

12 December 2020

Partition coefficients and surface areas of some alkylbenzenes

1 reference

12 December 2020

Thermodynamics of distribution of p-substituted phenols between aqueous solution and organic solvents and phospholipid vesicles

1 reference

12 December 2020

Thermodynamic Analysis of Structure-Activity Relationships of Drugs: Prediction of Optimal Structure

1 reference

12 December 2020

Transport of alkyl Homologs Across Synthetic and Biological Membranes: A new Model for Chain Length-Activity Relationships

1 reference

12 December 2020

Chromatography in studies of quantitative structure-activity relationships

1 reference

12 December 2020

SUBSTITUENT CONSTANTS FOR ALIPHATIC FUNCTIONS OBTAINED FROM PARTITION COEFFICIENTS

1 reference

12 December 2020

Kinetic Analysis of Relationship between Partition Coefficient and Biological Response

1 reference

12 December 2020

Steric and lipophobic components of the hydrophobic fragmental constant

1 reference

12 December 2020

A correlation of thyroxine-like activity and chemical structure

1 reference

12 December 2020

Rates of transfer of organic protolytic solutes between an aqueous and an organic phase. V. The thermodynamics of mass transfer

1 reference

12 December 2020

Chromatographic hydrophobic parameters in correlation analysis of structure-activity relationships

1 reference

12 December 2020

Parachors in drug design

1 reference

12 December 2020

Influence of the structure of aliphatic substituents on the magnitude of the biological effect of substances

1 reference

12 December 2020

Stability of aspirin derivatives to hydrolysis

1 reference

12 December 2020

Application of diffusion theory to the relationship between partition coefficient and biological response

1 reference

12 December 2020

Dependence of hydrophobicity of apolar molecules on their molecular volume

1 reference

12 December 2020

Correlation of chromatographically obtained substituent constants and analgesic activity

1 reference

12 December 2020

The Partition of Organic Compounds Between Higher Alcohols and Water

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.3891/ACTA.CHEM.SCAND.05-0774

Identifiers

DOI

10.1289/EHP.8561203

1 reference

15 September 2017

1 reference

PMC publication ID

1568760

15 September 2017

PubMed publication ID

3905374

1 reference

PMC publication ID

1568760