(Q39840480)

15 September 2017

The antiproliferative cytostatic effects of a self-activating viridin prodrug (English)

1 reference

15 September 2017

10

1 reference

15 September 2017

7

Ralph Weissleder

1 reference

15 September 2017

Elena Aikawa

4

0 references

Rainer H Kohler

8

object named as

Rainer Kohler

1 reference

15 September 2017

6

Jose-Luiz Figueiredo

1 reference

15 September 2017

3

Hushan Yuan

1 reference

15 September 2017

11

Lee Josephson

1 reference

15 September 2017

Adam Smith

1

1 reference

15 September 2017

Joseph Blois

2

1 reference

15 September 2017

Christian Ellson

5

1 reference

15 September 2017

Michael B Yaffe

9

1 reference

15 September 2017

9 June 2009

1 reference

Molecular Cancer Therapeutics

15 September 2017

1 reference

15 September 2017

8

1 reference

15 September 2017

6

1 reference

15 September 2017

1666-1675

1 reference

describes a project that uses

15 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2740925/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Slow self-activation enhances the potency of viridin prodrugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Synthesis and structure-activity relationships of ring-opened 17-hydroxywortmannins: potent phosphoinositide 3-kinase inhibitors with improved properties and anticancer efficacy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Fate of a bioactive fluorescent wortmannin derivative in cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Prodrug strategies in anticancer chemotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

The anti-angiogenic basis of metronomic chemotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

The viridin family of steroidal antibiotics.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Synthesis and in vitro evaluation of new wortmannin esters: potent inhibitors of phosphatidylinositol 3-kinase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Wortmannin-C20 conjugates generate wortmannin

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Chemistry and biology of wortmannin

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Polysaccharides as drug carriers: biodisposition of fluorescein-labeled dextrans in mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Covalent Reactions of Wortmannin under Physiological Conditions

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740925

Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues

2 December 2018

1 reference

12 December 2020

In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin

1 reference

12 December 2020

Studies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin and related analogs

1 reference

12 December 2020

Potent inhibition of angiogenesis by wortmannin, a fungal metabolite

1 reference

12 December 2020

Practicalities of drugging the phosphatidylinositol-3-kinase/Akt cell survival signaling pathway

1 reference

12 December 2020

10.1158/1535-7163.MCT-08-1012

Identifiers

DOI

1 reference

release_vhgv7dp6zrcvbnsmm3fawi4k74

15 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vhgv7dp6zrcvbnsmm3fawi4k74

24 November 2022

mapped directly with Wikidata item

1 reference

15 September 2017

PubMed publication ID

19509266

1 reference