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Pim-1 plays a pivotal role in hypoxia-induced chemoresistance.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
title
Pim-1 plays a pivotal role in hypoxia-induced chemoresistance
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
hypoxia
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author
Mong-Hong Lee
series ordinal
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author name string
J Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
M Kobayashi
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
S Darmanin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Y Qiao
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
C Gully
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
R Zhao
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
S C Yeung
series ordinal
7
1 reference
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Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
language of work or name
English
0 references
publication date
1 June 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
28
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
28
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
2581-2592
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/onc.2009.124
0 references
cites work
Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation
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PubMed Central
reference URL
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22 September 2017
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
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PubMed Central
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22 September 2017
Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours
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PubMed Central
reference URL
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22 September 2017
Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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22 September 2017
Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
22 September 2017
Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.
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22 September 2017
Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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22 September 2017
The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
22 September 2017
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
22 September 2017
Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
22 September 2017
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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22 September 2017
Perspectives on oxygen sensing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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22 September 2017
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
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22 September 2017
Hypoxia and drug resistance
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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22 September 2017
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
22 September 2017
The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
25 September 2017
Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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25 September 2017
Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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17 June 2018
Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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17 June 2018
Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
17 June 2018
The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
17 June 2018
Study of cell kinetics in anaplastic thyroid carcinoma transplanted to nude mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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17 June 2018
Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
17 June 2018
PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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20 August 2018
Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Pim-1 expression in prostatic intraepithelial neoplasia and human prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
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20 August 2018
[Pim-1 induced by hypoxia is involved in drug resistance and tumorigenesis of solid tumor cells].
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Pim-1 phosphorylates the DNA binding domain of c-Myb.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Developmental expression of pim kinases suggests functions also outside of the hematopoietic system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358117
retrieved
20 August 2018
Hypoxia induces AP-1-regulated genes and AP-1 transcription factor binding in human endothelial and other cell types
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FONC.2009.124
retrieved
31 March 2020
Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FONC.2009.124
retrieved
31 March 2020
Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19483729
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/ONC.2009.124
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMC publication ID
3358117
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed publication ID
19483729
1 reference
stated in
Europe PubMed Central
PMC publication ID
3358117
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19483729%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
ResearchGate publication ID
26254612
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