(Q39846393)

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Mutagenesis of varicella-zoster virus glycoprotein B: putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo

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scholarly article

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Europe PubMed Central

15 September 2017

Mutagenesis of varicella-zoster virus glycoprotein B: putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo (English)

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Europe PubMed Central

15 September 2017

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Charles Grose

5

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6

object named as

Ann M Arvin

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Europe PubMed Central

15 September 2017

author name string

Stefan L Oliver

1

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Europe PubMed Central

15 September 2017

Marvin Sommer

2

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Europe PubMed Central

15 September 2017

Leigh Zerboni

3

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Europe PubMed Central

15 September 2017

Jaya Rajamani

4

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Europe PubMed Central

15 September 2017

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publication date

27 May 2009

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Europe PubMed Central

15 September 2017

number of pages

12

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Journal of Virology

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Europe PubMed Central

15 September 2017

83

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Europe PubMed Central

15 September 2017

15

1 reference

Europe PubMed Central

15 September 2017

7495-7506

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Europe PubMed Central

15 September 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2708640/fullTextXML

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Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infection

1 reference

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22 September 2017

Entry of herpesviruses into mammalian cells

1 reference

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A self-excisable infectious bacterial artificial chromosome clone of varicella-zoster virus allows analysis of the essential tegument protein encoded by ORF9.

1 reference

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22 September 2017

Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies

1 reference

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22 September 2017

Random linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein B

1 reference

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22 September 2017

Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins

1 reference

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The multipartite system that mediates entry of herpes simplex virus into the cell

1 reference

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22 September 2017

Proteolytic cleavage of glycoprotein B is dispensable for in vitro replication, but required for syncytium formation of pseudorabies virus.

1 reference

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22 September 2017

Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity

1 reference

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22 September 2017

Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4.

1 reference

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22 September 2017

Mutational evidence of internal fusion loops in herpes simplex virus glycoprotein B

1 reference

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22 September 2017

Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infection

1 reference

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22 September 2017

Crystal structure of glycoprotein B from herpes simplex virus 1.

1 reference

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22 September 2017

Varicella-zoster virus open reading frame 10 is a virulence determinant in skin cells but not in T cells in vivo

1 reference

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22 September 2017

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

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T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection

1 reference

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22 September 2017

Varicella-Zoster virus pathogenesis and immunobiology: new concepts emerging from investigations with the SCIDhu mouse model

1 reference

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Varicella: report of two fatal cases with necropsy, virus isolation, and serologic studies

1 reference

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Herpesvirus entry: an update

1 reference

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22 September 2017

Differentiation of varicella-zoster virus ORF47 protein kinase and IE62 protein binding domains and their contributions to replication in human skin xenografts in the SCID-hu mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Mutational Analysis of Open Reading Frames 62 and 71, Encoding the Varicella-Zoster Virus Immediate-Early Transactivating Protein, IE62, and Effects on Replication In Vitro and in Skin Xenografts in the SCID-hu Mouse In Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Proteolytic processing of human cytomegalovirus glycoprotein B is dispensable for viral growth in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Role of the varicella-zoster virus gB cytoplasmic domain in gB transport and viral egress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Varicella-zoster Virus gB and gE coexpression, but not gB or gE alone, leads to abundant fusion and syncytium formation equivalent to those from gH and gL coexpression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Cytoplasmic domain signal sequences that mediate transport of varicella-zoster virus gB from the endoplasmic reticulum to the Golgi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708640

22 September 2017

The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse

1 reference

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Attenuation of the vaccine Oka strain of varicella-zoster virus and role of glycoprotein C in alphaherpesvirus virulence demonstrated in the SCID-hu mouse

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Proteolytic cleavage of bovine herpesvirus 1 (BHV-1) glycoprotein gB is not necessary for its function in BHV-1 or pseudorabies virus

1 reference

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A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

1 reference

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Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu mice

1 reference

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22 September 2017

Characterization of the envelope proteins of pseudorabies virus

1 reference

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22 September 2017

Assembly and processing of the disulfide-linked varicella-zoster virus glycoprotein gpII(140).

1 reference

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22 September 2017

The complete DNA sequence of varicella-zoster virus

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Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion

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1 reference

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22 September 2017

Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetration

1 reference

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22 September 2017

Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration, but only gII is involved in membrane fusion

1 reference

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Development of a live attenuated varicella vaccine

1 reference

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Host cell proteases controlling virus pathogenicity

1 reference

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25 September 2017

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

1 reference

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Identification of the gB homologues of equine herpesvirus types 1 and 4 as disulphide-linked heterodimers and their characterization using monoclonal antibodies

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Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1 reference

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Expression of bovine herpesvirus type 1 glycoprotein gI in transfected bovine cells induces spontaneous cell fusion

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Synthesis and processing of the major envelope glycoprotein of murine cytomegalovirus

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Domains of herpes simplex virus I glycoprotein B that function in virus penetration, cell-to-cell spread, and cell fusion

1 reference

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Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

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The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses

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Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts

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Identification of the authentic varicella-zoster virus gB (gene 31) initiating methionine overlapping the 3' end of gene 30.

1 reference

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Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus

1 reference

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20 August 2018

Proteolytic processing of human cytomegalovirus glycoprotein B (gpUL55) is mediated by the human endoprotease furin.

1 reference

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20 August 2018

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19474103

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VZV gB endocytosis and Golgi localization are mediated by YXXphi motifs in its cytoplasmic domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19474103

12 December 2020

based on heuristic

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Live attenuated varicella vaccine: Immunization of healthy children with the OKA strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19474103

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00400-09

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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