(Q39856357)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary ¹³C flux analysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

Pichia pastoris

1 reference

3

1 reference

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24 February 2020

Pau Ferrer

7

1 reference

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24 February 2020

Joan Albiol

8

1 reference

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24 February 2020

Aljoscha Wahl

9

1 reference

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24 February 2020

author name string

Joel Jordà

1

1 reference

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24 February 2020

Camilo Suarez

2

1 reference

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24 February 2020

Angela ten Pierick

4

1 reference

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24 February 2020

Joseph J Heijnen

5

1 reference

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24 February 2020

Walter van Gulik

6

1 reference

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24 February 2020

publication date

28 February 2013

1 reference

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24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

7

1 reference

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24 February 2020

page(s)

17

1 reference

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Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures.

24 February 2020

cites work

1 reference

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22 September 2017

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Protein secretion in Pichia pastoris and advances in protein production

22 September 2017

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22 September 2017

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22 September 2017

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A multi-level study of recombinant Pichia pastoris in different oxygen conditions.

22 September 2017

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Limitations in Xylose-FermentingSaccharomyces cerevisiae, Made Evident through Comprehensive Metabolite Profiling and Thermodynamic Analysis

22 September 2017

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Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement

22 September 2017

1 reference

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Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst.

22 September 2017

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Recent patents on the Pichia pastoris expression system: expanding the toolbox for recombinant protein production

22 September 2017

1 reference

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Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris.

22 September 2017

1 reference

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Genome sequence of the recombinant protein production host Pichia pastoris

22 September 2017

1 reference

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anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data

22 September 2017

1 reference

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Regulation of methanol utilisation pathway genes in yeasts

22 September 2017

1 reference

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Systematic assignment of thermodynamic constraints in metabolic network models

22 September 2017

1 reference

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Metabolic networks in motion: 13C-based flux analysis

22 September 2017

1 reference

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Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data

22 September 2017

1 reference

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Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: a review

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

New tools for mass isotopomer data evaluation in (13)C flux analysis: mass isotope correction, data consistency checking, and precursor relationships.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Metabolic flux profiling of Escherichia coli mutants in central carbon metabolism using GC-MS.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Recent advances in the expression of foreign genes in Pichia pastoris

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Physiology of yeasts in relation to biomass yields

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

In vivo stationary flux analysis by 13C labeling experiments.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Substrate cycles in Penicillium chrysogenum quantified by isotopic non-stationary flux analysis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Development of quantitative metabolomics for Pichia pastoris.

17 June 2018

1 reference

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Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis

17 June 2018

1 reference

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Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids. An efficient analytical tool to investigate intermediary metabolism.

17 June 2018

1 reference

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Methanol oxidation and assimilation in Hansenula polymorpha. An analysis by 13C n.m.r. in vivo

17 June 2018

1 reference

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Optimization of the heterologous production of a Rhizopus oryzae lipase in Pichia pastoris system using mixed substrates on controlled fed-batch bioprocess.

17 June 2018

1 reference

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Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production

20 August 2018

1 reference

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Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae.

20 August 2018

1 reference

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Quantitative physiology of Pichia pastoris during glucose-limited high-cell density fed-batch cultivation for recombinant protein production

20 August 2018

1 reference

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Intracellular metabolite determination in the presence of extracellular abundance: Application to the penicillin biosynthesis pathway in Penicillium chrysogenum

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Engineering the Pichia pastoris methanol oxidation pathway for improved NADH regeneration during whole-cell biotransformation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Quantitative evaluation of intracellular metabolite extraction techniques for yeast metabolomics

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Identification and characterization of a complete carnitine biosynthesis pathway in Candida albicans

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

The effect of temperature on the proteome of recombinant Pichia pastoris.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Linear constraint relations in biochemical reaction systems: I. Classification of the calculability and the balanceability of conversion rates.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Application of macroscopic balances to the identification of gross measurement errors

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady-state and highly dynamic conditions

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Metabolic flux profiling of Pichia pastoris grown on glycerol/methanol mixtures in chemostat cultures at low and high dilution rates.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Experimental design principles for isotopically instationary 13C labeling experiments.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Non-repressing carbon sources for alcohol oxidase (AOX1) promoter of Pichia pastoris

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Impact of transamination reactions and protein turnover on labeling dynamics in (13)C-labeling experiments

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

MIRACLE: mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Metabolic isotopomer labeling systems. Part I: global dynamic behavior.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3626722

Stoichiometry and compartmentation of NADH metabolism inSaccharomyces cerevisiae

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1752-0509-7-17

Recombinant protein production in yeasts

21 January 2018

1 reference

12 December 2020

Stationary versus non-stationary 13C-MFA: A comparison using a consistent dataset

1 reference

12 December 2020

Quantification of Intracellular Metabolic Fluxes from Fractional Enrichment and13C–13C Coupling Constraints on the Isotopomer Distribution in Labeled Biomass Components

1 reference

12 December 2020

Sorbitol co-feeding reduces metabolic burden caused by the overexpression of a Rhizopus oryzae lipase in Pichia pastoris

1 reference

12 December 2020

Improved rapid sampling for in vivo kinetics of intracellular metabolites in Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1186/1752-0509-7-17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json

journals/bmcsb/JordaSCPHGFAW13

24 February 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

23448228

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448228%20AND%20SRC:MED&resulttype=core&format=json