(Q39856747)

15 September 2017

title

Induced pluripotent stem cells: opportunities as research and development tools in 21st century drug discovery (English)

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15 September 2017

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Rebecca K Rowntree

1

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15 September 2017

John D McNeish

series ordinal

2

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15 September 2017

publication date

1 July 2010

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15 September 2017

published in

Regenerative Medicine

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15 September 2017

volume

5

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15 September 2017

issue

4

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15 September 2017

page(s)

557-568

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

15 September 2017

cites work

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21 January 2018

iPS cells: potent stuff.

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

21 January 2018

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Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

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Generation of mouse induced pluripotent stem cells without viral vectors

21 January 2018

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Induced pluripotent stem cells generated without viral integration

21 January 2018

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Human induced pluripotent stem cells free of vector and transgene sequences

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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A chemical platform for improved induction of human iPSCs

21 January 2018

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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

21 January 2018

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Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

21 January 2018

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

21 January 2018

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Human induced pluripotent stem cells on autologous feeders

21 January 2018

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A reprogrammable mouse strain from gene-targeted embryonic stem cells

21 January 2018

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Visualization of omics data for systems biology

21 January 2018

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Induced pluripotent stem cells in regenerative medicine: an argument for continued research on human embryonic stem cells

21 January 2018

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Stem cells as screening tools in drug discovery

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

21 January 2018

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MicroRNA profiling of human-induced pluripotent stem cells

21 January 2018

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Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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Stem cell therapies: California dreamin'?

21 January 2018

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Pharmacological potential of embryonic stem cells

21 January 2018

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Embryonic stem cells in drug discovery

21 January 2018

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Embryonic stem cells as a source of models for drug discovery.

21 January 2018

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Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

21 January 2018

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High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors

21 January 2018

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Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry

21 January 2018

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Human embryonic stem cell models of Huntington disease.

21 January 2018

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Generation of pig induced pluripotent stem cells with a drug-inducible system

21 January 2018

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Derivation of induced pluripotent stem cells from pig somatic cells

21 January 2018

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Generation of induced pluripotent stem cell lines from Tibetan miniature pig.

21 January 2018

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Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts

21 January 2018

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

21 January 2018

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Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.

21 January 2018

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Generation of induced pluripotent stem cells from human cord blood.

21 January 2018

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Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

21 January 2018

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Marked differences in differentiation propensity among human embryonic stem cell lines

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Induced pluripotent stem cells and the stability of the differentiated state

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Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

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Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.

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Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes

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Generation of pluripotent stem cells from patients with type 1 diabetes

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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

21 January 2018

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Restricted ethnic diversity in human embryonic stem cell lines

21 January 2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

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Induced pluripotent stem cells from a spinal muscular atrophy patient

21 January 2018

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Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells

21 January 2018

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Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells

21 January 2018

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Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells.

21 January 2018

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Generation of functional human hepatic endoderm from human induced pluripotent stem cells

21 January 2018

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Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

21 January 2018

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Homologous recombination in human embryonic stem cells.

21 January 2018

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 January 2018

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Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 January 2018

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Genome-scale loss-of-function screening with a lentiviral RNAi library

21 January 2018

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Technical challenges in using human induced pluripotent stem cells to model disease

21 January 2018

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Cytochrome p450 and chemical toxicology

21 January 2018

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Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

21 January 2018

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Cardionomics: a new integrative approach for screening cardiotoxicity of drug candidates

21 January 2018

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Sudden death due to cardiac arrhythmias

21 January 2018

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Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

21 January 2018

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HLA-matching potential of an established human embryonic stem cell bank in China

21 January 2018

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Regulatory issues for personalized pluripotent cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/RME.10.36

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15 September 2017

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