(Q39860468)

English

Modification of alternative splicing of Mcl-1 pre-mRNA using antisense morpholino oligonucleotides induces apoptosis in basal cell carcinoma cells

scientific article published on 16 April 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 September 2017

Modification of alternative splicing of Mcl-1 pre-mRNA using antisense morpholino oligonucleotides induces apoptosis in basal cell carcinoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

author name string

Jeng-Jer Shieh

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Kuang-Ting Liu

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Shi-Wei Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Yi-Ju Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Tsu-Yi Hsieh

5

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

language of work or name

0 references

publication date

16 April 2009

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Journal of Investigative Dermatology

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Europe PubMed Central

PubMed publication ID

15 September 2017

129

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

2497-2506

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

https://scigraph.springernature.com/pub.10.1038/jid.2009.83

0 references

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

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Cell-permeable peptides induce dose- and length-dependent cytotoxic effects

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural insights into the degradation of Mcl-1 induced by BH3 domains

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

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Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of interleukin-6 in human basal cell carcinoma cell lines increases anti-apoptotic activity and tumorigenic potency.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

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Myeloid cell leukemia-1 as a therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense technology: a selective tool for gene expression regulation and gene targeting

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxic switch in mitochondrial myeloid cell leukemia factor-1/Mtd apoptotic rheostat contributes to human trophoblast cell death in preeclampsia

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Endo-Porter: a novel reagent for safe, effective delivery of substances into cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

BH3-ligand regulates access of MCL-1 to its E3 ligase

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Unique biology of Mcl-1: therapeutic opportunities in cancer

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulating the expression of disease genes with RNA-based therapy.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Mcl-1: a highly regulated cell death and survival controller

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.83

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/JID.2009.83

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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