(Q39862444)

15 September 2017

title

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy (English)

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15 September 2017

K Dredge

1

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15 September 2017

E Hammond

2

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K Davis

3

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15 September 2017

C P Li

4

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L Liu

5

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K Johnstone

6

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P Handley

7

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N Wimmer

8

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15 September 2017

T J Gonda

9

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15 September 2017

A Gautam

10

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V Ferro

11

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I Bytheway

12

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15 September 2017

publication date

9 April 2009

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Investigational New Drugs

15 September 2017

published in

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15 September 2017

volume

28

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15 September 2017

issue

3

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15 September 2017

page(s)

276-283

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https://scigraph.springernature.com/pub.10.1007/s10637-009-9245-5

15 September 2017

exact match

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cites work

Heparanase: one molecule with multiple functions in cancer progression

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12 December 2020

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

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12 December 2020

Involvement of stromal proteoglycans in tumour progression

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12 December 2020

Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance.

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12 December 2020

Angiogenesis assays: a critical overview

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12 December 2020

Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88).

1 reference

12 December 2020

Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: A comparative study of angiogenesis in Matrigel, collagen, fibrin, and plasma clot

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12 December 2020

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

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12 December 2020

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

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12 December 2020

Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells

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12 December 2020

Therapeutic options to target angiogenesis in human malignancies

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12 December 2020

PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.

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12 December 2020

Heparin derivatives as angiogenesis inhibitors

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12 December 2020

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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12 December 2020

Capsaicin inhibits in vitro and in vivo angiogenesis

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12 December 2020

A surface plasmon resonance-based solution affinity assay for heparan sulfate-binding proteins

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12 December 2020

Angiogenesis in cancer and other diseases

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12 December 2020

Novel drug development opportunities for heparin.

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12 December 2020

Tumorigenesis and the angiogenic switch

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12 December 2020

High-performance liquid chromatographic/mass spectrometric studies on the susceptibility of heparin species to cleavage by heparanase

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12 December 2020

Heparanase induces VEGF C and facilitates tumor lymphangiogenesis

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12 December 2020

Roles of heparan-sulphate glycosaminoglycans in cancer

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12 December 2020

10.1007/S10637-009-9245-5

Identifiers

DOI

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15 September 2017

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