(Q39863634)

English

Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis

scientific article published on January 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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1 reference

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author name string

Koji Kawata

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Ryuhei Shimazaki

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Satoshi Okabe

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

publication date

1 January 2009

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Environmental and Molecular Mutagenesis

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Europe PubMed Central

PubMed publication ID

15 September 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

46-59

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Cell cycle regulation by the Cdc25 phosphatase family

1 reference

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21 January 2018

Mechanism of arsenic carcinogenesis: an integrated approach

1 reference

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Cadmium carcinogenesis

1 reference

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The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents

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Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

1 reference

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Genomic and proteomic profiling of responses to toxic metals in human lung cells

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DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5.

1 reference

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7 January 2021

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The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells

1 reference

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Applications of gene arrays in environmental toxicology: fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene

1 reference

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Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

1 reference

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Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells

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Amino-terminal-derived JNK fragment alters expression and activity of c-Jun, ATF2, and p53 and increases H2O2-induced cell death

1 reference

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Simultaneous measurement of ERK, p38, and JNK MAP kinase cascades in vascular smooth muscle cells

1 reference

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7 January 2021

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Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium

1 reference

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Comparison of microbial tests for the detection of heavy metal genotoxicity.

1 reference

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Metabolic activation of chemicals to mutagenic carcinogens by human hepatoma microsomal extracts in Chinese hamster ovary cells (in vitro)

1 reference

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Nickel essentiality, toxicity, and carcinogenicity

1 reference

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Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

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7 January 2021

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WAF1, a potential mediator of p53 tumor suppression

1 reference

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7 January 2021

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Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage.

1 reference

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Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

1 reference

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7 January 2021

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Spin trapping of free radicals produced from nitrosoamine carcinogens

1 reference

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Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype

1 reference

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Cell cycle regulation of breast cancer cells through estrogen-induced activities of ERK and Akt protein kinases

1 reference

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7 January 2021

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Lung cancer incidence among Norwegian nickel-refinery workers 1953-2000.

1 reference

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7 January 2021

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

1 reference

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Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

1 reference

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7 January 2021

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Current aspects in metal genotoxicity

1 reference

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7 January 2021

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Expression of pituitary-tumour transforming gene in colorectal tumours

1 reference

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7 January 2021

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Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

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Vitamin C protects HL60 and U266 cells from arsenic toxicity.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

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Classification of heavy-metal toxicity by human DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

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Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Time course of cell cycle-related protein expression in diethylnitrosamine-initiated rat liver

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

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Benzo[a]pyrene and glycine N-methyltransferse interactions: gene expression profiles of the liver detoxification pathway

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential activation of ERK, JNK/SAPK and P38/CSBP/RK map kinase family members during the cellular response to arsenite

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

1 reference

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based on heuristic

inferred from DOI database lookup

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

1 reference

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7 January 2021

based on heuristic

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Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

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Biphasic estradiol-induced AKT phosphorylation is modulated by PTEN via MAP kinase in HepG2 cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen-Like Activity of Metals in Mcf-7 Breast Cancer Cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

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Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer

1 reference

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The influence of follicle size, FSH-enriched maturation medium, and early cleavage on bovine oocyte maternal mRNA levels.

1 reference

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based on heuristic

inferred from DOI database lookup

Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of MAPKs in human bronchial epithelial cells exposed to metals.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Metal carcinogenesis: mechanistic implications

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

PTTG mRNA expression in primary breast cancer: a prognostic marker for lymph node invasion and tumor recurrence

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of MAP kinases by hexavalent chromium, manganese and nickel in human lung epithelial cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Metals, toxicity and oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Free radicals, metals and antioxidants in oxidative stress-induced cancer

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Genotoxic methylating agents modulate extracellular signal regulated kinase activity through MEK-dependent, glutathione-, and DNA methylation-independent mechanisms in lung epithelial cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

The signaling mechanism of ROS in tumor progression

1 reference

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based on heuristic

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Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas

1 reference

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Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

1 reference

https://api.crossref.org/works/10.1002%2FEM.20438

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EM.20438

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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