(Q39867585)

15 September 2017

title

Screening of a PKC zeta-specific kinase inhibitor PKCzI257.3 which inhibits EGF-induced breast cancer cell chemotaxis (English)

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15 September 2017

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Jing Wu

1

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15 September 2017

Baogang Zhang

2

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15 September 2017

Min Wu

3

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15 September 2017

Hongyan Li

4

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15 September 2017

Ruifang Niu

5

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15 September 2017

Guoguang Ying

6

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15 September 2017

Ning Zhang

7

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15 September 2017

language of work or name

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27 March 2009

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Investigational New Drugs

15 September 2017

published in

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15 September 2017

volume

28

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15 September 2017

issue

3

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15 September 2017

page(s)

268-275

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https://scigraph.springernature.com/pub.10.1007/s10637-009-9242-8

15 September 2017

exact match

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cites work

Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions

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12 December 2020

Down-regulation of PKCzeta expression inhibits chemotaxis signal transduction in human lung cancer cells

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12 December 2020

The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells

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12 December 2020

Pivotal Advance: PKCzeta is required for migration of macrophages

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12 December 2020

PI 3-kinases and PTEN: how opposites chemoattract

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12 December 2020

G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation

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12 December 2020

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

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12 December 2020

Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells

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12 December 2020

Critical determinants of metastasis

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12 December 2020

A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases

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12 December 2020

The role of chemokines in melanoma tumor growth and metastasis

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12 December 2020

The therapeutic role of targeting protein kinase C in solid and hematologic malignancies

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12 December 2020

Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway.

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12 December 2020

Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells

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12 December 2020

Organ selectivity in metastasis: regulation by chemokines and their receptors

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12 December 2020

Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.

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12 December 2020

Competitive inhibition by diacylglycerol of specific phorbol ester binding

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12 December 2020

Cofilin promotes actin polymerization and defines the direction of cell motility

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12 December 2020

Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.

1 reference

12 December 2020

Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C.

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12 December 2020

Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42

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12 December 2020

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

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12 December 2020

Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway

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12 December 2020

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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12 December 2020

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

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12 December 2020

PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation

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12 December 2020

Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis

1 reference

12 December 2020

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

1 reference

12 December 2020

RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing

1 reference

12 December 2020

PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways

1 reference

12 December 2020

10.1007/S10637-009-9242-8

Identifiers

DOI

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15 September 2017

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