(Q39875291)

15 September 2017

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Homocysteine and Alzheimer's Disease: Evidence for a Causal Link from Mendelian Randomization (English)

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15 September 2017

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Qingting Hu

1

1 reference

15 September 2017

Wenhui Teng

2

1 reference

15 September 2017

Jiajia Li

3

1 reference

15 September 2017

Fangfang Hao

4

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15 September 2017

Naidong Wang

5

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15 September 2017

publication date

22 March 2016

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Journal of Alzheimer's Disease

15 September 2017

published in

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15 September 2017

volume

52

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15 September 2017

issue

2

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15 September 2017

page(s)

747-756

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Epidemiology of Alzheimer disease

15 September 2017

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The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies

21 January 2018

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Associations between Homocysteine, Folic Acid, Vitamin B12 and Alzheimer's Disease: Insights from Meta-Analyses

21 January 2018

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Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression.

21 January 2018

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Hyperhomocysteinemia and Alzheimer's disease: A systematic review

21 January 2018

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Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

21 January 2018

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Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis

21 January 2018

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Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias

21 January 2018

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Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study

21 January 2018

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Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

21 January 2018

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Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

21 January 2018

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Age- and gender-specific reference values of estimated GFR in Caucasians: the Nijmegen Biomedical Study.

21 January 2018

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The Cardiovascular Health Study: design and rationale

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The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

21 January 2018

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The Rotterdam Study: 2012 objectives and design update

21 January 2018

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Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women

21 January 2018

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Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

21 January 2018

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Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway

21 January 2018

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Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women

21 January 2018

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Re: Estimation of Bias in Nongenetic Observational Studies Using “Mendelian Triangulation” by Bautista et al

21 January 2018

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Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.

21 January 2018

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Meta-analysis of the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to Alzheimer's disease

21 January 2018

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Association between the MTHFR gene and Alzheimer's disease: a meta-analysis

21 January 2018

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Association of methylenetetrahydrofolate reductase polymorphisms with susceptibility to Alzheimer's disease

21 January 2018

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Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease

21 January 2018

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The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease.

21 January 2018

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ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia

21 January 2018

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Folate, homocysteine, vitamin B12, and polymorphisms of genes participating in one-carbon metabolism in late-onset Alzheimer's disease patients and healthy controls

21 January 2018

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Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.

21 January 2018

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The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population

21 January 2018

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Is MTHFR polymorphism a risk factor for Alzheimer's disease like APOE?

21 January 2018

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Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men.

21 January 2018

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Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans

21 January 2018

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Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk

21 January 2018

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Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease.

21 January 2018

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Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland

21 January 2018

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Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method

21 January 2018

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The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and vascular dementia.

21 January 2018

1 reference

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Plasma folate, vitamin B(12), and total homocysteine and homozygosity for the C677T mutation of the 5,10-methylene tetrahydrofolate reductase gene in patients with Alzheimer's dementia. A case-control study.

21 January 2018

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Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease

21 January 2018

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Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment

21 January 2018

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Methylenetetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms in two genetically and diagnostically distinct cohort of Alzheimer patients

21 January 2018

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Genetic analysis of vascular factors in Alzheimer's disease

21 January 2018

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Association of MTHFR gene polymorphism C677T with susceptibility to late-onset Alzheimer's disease

21 January 2018

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Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia.

21 January 2018

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Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia

21 January 2018

1 reference

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Intergenotypic variation of Vitamin B12 and Folate in AD: In north indian population

21 January 2018

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C677T methylentetrahydrofulate reductase and angiotensin converting enzyme gene polymorphisms in patients with Alzheimer's disease in Iranian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

Mendelian randomisation applied to drug development in cardiovascular disease: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

Homocysteine Induced Cerebrovascular Dysfunction: A Link to Alzheimer's Disease Etiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150977

21 January 2018

Identifiers

DOI

10.3233/JAD-150977

1 reference

15 September 2017

1 reference