Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q39877190)
Watch
English
Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
title
Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
main subject
polyposis
1 reference
based on heuristic
inferred from title
author
Yinghui Mao
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
author name string
Jiayin Zhang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
Roberto Neisa
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
publication date
4 March 2009
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
published in
Molecular Biology of the Cell
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
volume
20
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
page(s)
2381-2388
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
cites work
Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Novel self-association of the APC molecule affects APC clusters and cell migration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Examining the link between chromosomal instability and aneuploidy in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Does aneuploidy cause cancer?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Spindle checkpoint requires Mad1-bound and Mad1-free Mad2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Aneuploid colon cancer cells have a robust spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
A role for the Adenomatous Polyposis Coli protein in chromosome segregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Mutations of mitotic checkpoint genes in human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Lessons from hereditary colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Dimer formation by an N-terminal coiled coil in the APC protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Cell cycle extracts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Feedback control of mitosis in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
22 September 2017
Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
25 September 2017
Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
25 September 2017
In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
20 August 2018
The Mad2 spindle checkpoint protein has two distinct natively folded states.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
20 August 2018
The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
20 August 2018
CENP-E as an essential component of the mitotic checkpoint in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
20 August 2018
Association between wild type and mutant APC gene products.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675618
retrieved
20 August 2018
Mutations in the APC tumour suppressor gene cause chromosomal instability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19261806
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1091/MBC.E08-12-1206
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
PMCID
2675618
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
PubMed ID
19261806
1 reference
stated in
Europe PubMed Central
PMCID
2675618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
