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Physical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27.
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22 October 2019
title
Physical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27
(English)
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Europe PubMed Central
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22 October 2019
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C A Panagiotidis
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1
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Europe PubMed Central
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191212
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8995681%20AND%20SRC:MED&resulttype=core&format=json
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22 October 2019
E K Lium
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2
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191212
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22 October 2019
S J Silverstein
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3
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22 October 2019
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English
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publication date
1 February 1997
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22 October 2019
published in
Journal of Virology
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Europe PubMed Central
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191212
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22 October 2019
volume
71
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Europe PubMed Central
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191212
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8995681%20AND%20SRC:MED&resulttype=core&format=json
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22 October 2019
issue
2
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Europe PubMed Central
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191212
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22 October 2019
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1547-1557
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22 October 2019
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Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters
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The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.
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22 September 2017
Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein
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22 September 2017
The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.
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22 September 2017
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.
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22 September 2017
Separation of primary structural components conferring autoregulation, transactivation, and DNA-binding properties to the herpes simplex virus transcriptional regulatory protein ICP4
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22 September 2017
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22 September 2017
The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule
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22 September 2017
Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities
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22 September 2017
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
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22 September 2017
Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient
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22 September 2017
The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection
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22 September 2017
Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene
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22 September 2017
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
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22 September 2017
Codons 262 to 490 from the herpes simplex virus ICP4 gene are sufficient to encode a sequence-specific DNA binding protein
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22 September 2017
Nucleotides within both proximal and distal parts of the consensus sequence are important for specific DNA recognition by the herpes simplex virus regulatory protein ICP4
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22 September 2017
The interaction of ICP4 with cell/infected-cell factors and its state of phosphorylation modulate differential recognition of leader sequences in herpes simplex virus DNA
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Isolation and characterization of a functional cDNA encoding ICP0 from herpes simplex virus type 1
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22 September 2017
Human papillomavirus 16 E7 protein is associated with the nuclear matrix
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22 September 2017
Purification of the DNA binding domain of herpes simplex virus type 1 immediate-early protein Vmw175 as a homodimer and extensive mutagenesis of its DNA recognition site
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22 September 2017
Biologic properties and nucleotide sequence analysis of human papillomavirus type 51
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22 September 2017
ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated
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22 September 2017
Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing
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22 September 2017
Differences in the poly(ADP-ribosyl)ation patterns of ICP4, the herpes simplex virus major regulatory protein, in infected cells and in isolated nuclei
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22 September 2017
Herpes simplex viruses with mutations in the gene encoding ICP0 are defective in gene expression
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retrieved
22 September 2017
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Characteristics of a human cell line transformed by DNA from human adenovirus type 5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Characterization of transcription-deficient temperature-sensitive mutants of herpes simplex virus type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Molecular genetics of herpes simplex virus: Demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
22 September 2017
Control of transcription termination by RNA-binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
25 September 2017
pALEX, a dual-tag prokaryotic expression vector for the purification of full-length proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Poly(ADP-ribosyl)ation of a herpes simplex virus immediate early polypeptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Co-ordinate regulation of herpes simplex virus gene expression is mediated by the functional interaction of two immediate early gene products
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
The products of herpes simplex virus type 1 (HSV-1) immediate early genes 1, 2 and 3 can activate HSV-1 gene expression in trans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
The DNA-binding properties of the major regulatory protein alpha 4 of herpes simplex viruses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Redistribution of nuclear ribonucleoprotein antigens during herpes simplex virus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Interaction of cell and virus proteins with DNA sequences encompassing the promoter/regulatory and leader regions of the herpes simplex virus thymidine kinase gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Characterization of DNA-protein complex formation in nuclear extracts with a sequence from the herpes simplex virus thymidine kinase gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Transactivation by herpes simplex virus proteins ICP4 and ICPO in vaccinia virus infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
A predictive model for DNA recognition by the herpes simplex virus protein ICP4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
The herpes simplex virus immediate-early protein ICP27 stimulates the transcription of cellular Alu repeated sequences by increasing the activity of transcription factor TFIIIC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
15 June 2018
Relationship of the expression of the S20 and L34 ribosomal proteins to polyamine biosynthesis in Escherichia coli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
20 August 2018
Herpes simplex virus induces a processing factor that stimulates poly(A) site usage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191212
retrieved
20 August 2018
HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8995681
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Acid connections
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8995681
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
191212
1 reference
stated in
Europe PubMed Central
PMCID
191212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8995681%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
PubMed ID
8995681
1 reference
stated in
Europe PubMed Central
PMCID
191212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8995681%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
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