(Q39881840)

15 September 2017

title

Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer (English)

1 reference

15 September 2017

1 reference

Yan-Jie Zhang

1

1 reference

15 September 2017

Shu-Liang Zhao

2

1 reference

15 September 2017

Xiao-Qing Tian

3

1 reference

15 September 2017

Dan-Feng Sun

4

1 reference

15 September 2017

Hua Xiong

5

1 reference

15 September 2017

Qiang Dai

6

1 reference

15 September 2017

Xiao-Qiang Li

7

1 reference

15 September 2017

Jing-Yuan Fang

8

1 reference

15 September 2017

publication date

20 February 2009

1 reference

International Journal of Colorectal Disease

15 September 2017

published in

1 reference

15 September 2017

volume

24

1 reference

15 September 2017

issue

6

1 reference

15 September 2017

page(s)

629-639

1 reference

Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines

15 September 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00384-009-0664-8

Adjuvant treatment of colon cancer: past, present and future

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00384-009-0664-8

[Research advances on the relationship of PI3-kinase/Akt/mTOR pathway and epigenetic modification].

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00384-009-0664-8

Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer

21 January 2018

1 reference

12 December 2020

Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors

1 reference

12 December 2020

Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice

1 reference

12 December 2020

Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells

1 reference

12 December 2020

Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer

1 reference

12 December 2020

Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer

1 reference

12 December 2020

Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).

1 reference

12 December 2020

Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation

1 reference

12 December 2020

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

1 reference

12 December 2020

Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer

1 reference

12 December 2020

Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes

1 reference

12 December 2020

Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter

1 reference

12 December 2020

A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies

1 reference

12 December 2020

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

1 reference

12 December 2020

Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction

1 reference

12 December 2020

Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group

1 reference

12 December 2020

mTOR-targeted therapy of cancer with rapamycin derivatives

1 reference

12 December 2020

Mammalian target of rapamycin as a therapeutic target in oncology

1 reference

12 December 2020

DNA hypomethylation and human diseases.

1 reference

12 December 2020

5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer

1 reference

12 December 2020

mTOR and cancer therapy

1 reference

12 December 2020

Dosing of rapamycin is critical to achieve an optimal antiangiogenic effect against cancer.

1 reference

12 December 2020

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

1 reference

12 December 2020

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

1 reference

12 December 2020

Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

1 reference

12 December 2020

TOR signaling in growth and metabolism

1 reference

12 December 2020

Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma

1 reference

12 December 2020

New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.

1 reference

12 December 2020

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

1 reference

12 December 2020

Susceptibility for NSAIDs-induced apoptosis correlates to p53 gene status in gastric cancer cells

1 reference

12 December 2020

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

1 reference

12 December 2020

Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.

1 reference

12 December 2020

Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1.

1 reference

12 December 2020

Role of mTOR in solid tumor systems: a therapeutical target against primary tumor growth, metastases, and angiogenesis

1 reference

12 December 2020

1 reference

12 December 2020

DNA methyltransferases as targets for cancer therapy

1 reference

12 December 2020

Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells

1 reference

12 December 2020

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

12 December 2020

Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines

1 reference

12 December 2020

5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines

1 reference

12 December 2020

Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors

1 reference

12 December 2020

Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors

1 reference

12 December 2020

10.1007/S00384-009-0664-8

Identifiers

DOI

1 reference

15 September 2017

1 reference