(Q39884306)

15 September 2017

title

The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons (English)

1 reference

G protein-coupled receptor

15 September 2017

main subject

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9

Veerle Baekelandt

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15 September 2017

13

Bart De Strooper

1 reference

15 September 2017

Amantha Thathiah

1

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15 September 2017

Kurt Spittaels

2

1 reference

15 September 2017

Marcel Hoffmann

3

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15 September 2017

Mik Staes

4

1 reference

15 September 2017

Adrian Cohen

5

1 reference

15 September 2017

Katrién Horré

6

1 reference

15 September 2017

Mieke Vanbrabant

7

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15 September 2017

Frea Coun

8

1 reference

15 September 2017

André Delacourte

10

1 reference

15 September 2017

David F Fischer

11

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15 September 2017

Dirk Pollet

12

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15 September 2017

Pascal Merchiers

14

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15 September 2017

language of work or name

English

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publication date

1 February 2009

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15 September 2017

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15 September 2017

volume

323

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15 September 2017

issue

5916

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15 September 2017

page(s)

946-951

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Alzheimer's disease is a synaptic failure

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

A cell biological perspective on Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Amyloid-beta precursor protein processing in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Results of a high-resolution genome screen of 437 Alzheimer's disease families

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Premature ovarian aging in mice deficient for Gpr3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1160649

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1160649

1 reference

release_tylfvkuadvcdtodoi4cyqprfza

15 September 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tylfvkuadvcdtodoi4cyqprfza

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference