(Q39896591)

15 September 2017

title

Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells (English)

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15 September 2017

2

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15 September 2017

M Kochetkova

1

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15 September 2017

S R McColl

series ordinal

3

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15 September 2017

publication date

9 January 2009

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Cell Death & Differentiation

15 September 2017

published in

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15 September 2017

volume

16

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15 September 2017

issue

5

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15 September 2017

page(s)

664-673

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Chemokines, chemokine receptors, and cancer metastasis

15 September 2017

cites work

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Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells.

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New insights on the role of CXCR4 in cancer metastasis

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Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells.

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Regulation of Bcl-2 proteins during anoikis and amorphosis.

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JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

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Dissemination and growth of cancer cells in metastatic sites

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BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation

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Organ selectivity in metastasis: regulation by chemokines and their receptors

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Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells

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CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner

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Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

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Diverse transcriptional response of CD4+ T cells to stromal cell-derived factor SDF-1: cell survival promotion and priming effects of SDF-1 on CD4+ T cells

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Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

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Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

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Cell death: critical control points

21 January 2018

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Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development

21 January 2018

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Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy

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Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells

21 January 2018

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Involvement of chemokine receptors in organ-specific metastasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

7 January 2021

Chemokines and cancer

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.190

7 January 2021

Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

7 January 2021

Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

7 January 2021

CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

7 January 2021

Identifiers

DOI

10.1038/CDD.2008.190

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15 September 2017

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