(Q39899686)

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The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors (English)

1 reference

Europe PubMed Central

15 September 2017

author name string

Fei Huang

1

1 reference

Europe PubMed Central

15 September 2017

Ann Greer

2

1 reference

Europe PubMed Central

15 September 2017

Warren Hurlburt

3

1 reference

Europe PubMed Central

15 September 2017

Xia Han

4

1 reference

Europe PubMed Central

15 September 2017

Rameh Hafezi

5

1 reference

Europe PubMed Central

15 September 2017

Gayle M Wittenberg

6

1 reference

Europe PubMed Central

15 September 2017

Karen Reeves

7

1 reference

Europe PubMed Central

15 September 2017

Jiwen Chen

8

1 reference

Europe PubMed Central

15 September 2017

Douglas Robinson

9

1 reference

Europe PubMed Central

15 September 2017

Aixin Li

10

1 reference

Europe PubMed Central

15 September 2017

Francis Y Lee

11

1 reference

Europe PubMed Central

15 September 2017

Marco M Gottardis

12

1 reference

Europe PubMed Central

15 September 2017

Edwin Clark

13

1 reference

Europe PubMed Central

15 September 2017

Lee Helman

14

1 reference

Europe PubMed Central

15 September 2017

Ricardo M Attar

15

1 reference

Europe PubMed Central

15 September 2017

Ashok Dongre

16

1 reference

Europe PubMed Central

15 September 2017

Joan M Carboni

17

1 reference

Europe PubMed Central

15 September 2017

language of work or name

0 references

publication date

1 January 2009

1 reference

Europe PubMed Central

15 September 2017

Cancer Research

1 reference

Europe PubMed Central

15 September 2017

69

1 reference

Europe PubMed Central

15 September 2017

161-170

1 reference

Europe PubMed Central

15 September 2017

1

1 reference

Europe PubMed Central

15 September 2017

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin selectively activates STAT5b, but not STAT5a, via a JAK2-independent signalling pathway in Kym-1 rhabdomyosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhabdomyosarcoma--working out the pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors and their binding proteins: biological actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin-like growth factor 1 receptor in cancer: old focus, new future

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence-initiated reversal of drug resistance: specific role of cathepsin L.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of docetaxel response in human breast cancer by gene expression profiling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the IGF system in cancer growth and metastasis: overview and recent insights

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin-like growth factor system and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying reproducibility for differential proteomics: noise analysis for protein liquid chromatography-mass spectrometry of human serum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor is an independent predictor of a favorable outcome in early stage breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-resistant human laryngeal carcinoma cells have increased levels of cathepsin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical in vivo study of new insulin-like growth factor-I receptor--specific inhibitor in Ewing's sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein in carcinogenesis and cancer chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of complex peptide mixtures using FTMS and differential mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupting insulin-like growth factor signaling as a potential cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-inhibition of epidermal growth factor receptor and type 1 insulin-like growth factor receptor synergistically sensitizes human malignant glioma cells to CD95L-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of rituximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor binding proteins IGFBP3, IGFBP4, and IGFBP5 predict endocrine responsiveness in patients with ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of Insulin-Like Growth Factors (IGF) and IGF Binding Proteins by Cathepsin D1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic signatures to guide the use of chemotherapeutics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death--proliferative and anti-apoptotic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IGF‐1 receptor in cancer biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19117999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-0835

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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