(Q39900183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

estrogen-receptor negative breast cancer

3 March 2020

main subject

0 references

author name string

Anna C Cunningham-Edmondson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Steven K Hanks

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

publication date

7 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

Breast Cancer: Targets and Therapy

3 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

39-52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

3 March 2020

copyright license

start time

1 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3022348/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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22 September 2017

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Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

22 September 2017

1 reference

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22 September 2017

1 reference

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p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV

22 September 2017

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AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.

22 September 2017

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Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

22 September 2017

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22 September 2017

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The prognostic value of BCAR1 in patients with primary breast cancer.

22 September 2017

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Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

22 September 2017

1 reference

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Regulation of anoikis by Cdc42 and Rac1.

22 September 2017

1 reference

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p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells

22 September 2017

1 reference

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Relevance of breast cancer cell lines as models for breast tumours: an update

22 September 2017

1 reference

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Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells

22 September 2017

1 reference

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Src family kinases in tumor progression and metastasis

22 September 2017

1 reference

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How to target estrogen receptor-negative breast cancer?

22 September 2017

1 reference

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Src-dependent association of Cas and p85 phosphatidylinositol 3'-kinase in v-crk-transformed cells

22 September 2017

1 reference

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Epidermal growth factor stimulation can substitute for c-Src overexpression in promoting breast carcinoma invasion

22 September 2017

1 reference

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22 September 2017

1 reference

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Src in cancer: deregulation and consequences for cell behaviour

22 September 2017

1 reference

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Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate

22 September 2017

1 reference

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22 September 2017

1 reference

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Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Systematic variation in gene expression patterns in human cancer cell lines

22 September 2017

1 reference

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BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Mechanism of activation of protein kinase B by insulin and IGF-1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Why are estrogen-receptor-negative breast cancers more aggressive than the estrogen-receptor-positive breast cancers?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

A novel viral oncogene with structural similarity to phospholipase C

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

PI3K: downstream AKTion blocks apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Differentiation state and invasiveness of human breast cancer cell lines

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

CAS promotes invasiveness of Src-transformed cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Regulation and localization of CAS substrate domain tyrosine phosphorylation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022348

Src family kinase inhibitor PP2 restores the E-cadherin/catenin cell adhesion system in human cancer cells and reduces cancer metastasis

20 August 2018

1 reference

12 December 2020

1 reference

12 December 2020

p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts

1 reference

12 December 2020

C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis

1 reference

12 December 2020

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death

1 reference

12 December 2020

Identifiers

DOI

10.2147/BCTT.S6255

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367162%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

24367162

1 reference