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Src in cancer: deregulation and consequences for cell behaviour
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Src in cancer: deregulation and consequences for cell behaviour
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
author
Margaret Frame
series ordinal
1
object named as
Margaret C Frame
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
language of work or name
English
0 references
publication date
1 June 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
volume
1602
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
page(s)
114-130
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
cites work
The hunting of the Src
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular functions regulated by Src family kinases
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a molecularly cloned human c-src oncogene by using a replication-competent retroviral vector
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the transforming potential of p60c-src by a single amino acid change
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pp60c-src activation in human colon carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of pp60c-src protein kinase activity in human colon carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific differences in pp60c-src activity in human colorectal metastases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential pp60c-src activity in well and poorly differentiated human colon carcinomas and cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating SRC mutation in a subset of advanced human colon cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of mutation at codon 531 of SRC in advanced colorectal cancers from Italian patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the Src family of tyrosine kinases in mammary tumorigenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src activation in malignant and premalignant epithelia of Barrett's esophagus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of pp60c-src in human small cell and non-small cell lung carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant Elevation of Tyrosine-specific Phosphorylation in Human Gastric Cancer Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Src, receptor tyrosine kinases, and human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structures of Src-family tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insights into Src kinase functions: structural comparisons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A crystal milestone: the structure of regulated Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction: clamping down on Src activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Active and inactive protein kinases: structural basis for regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leucine 255 of Src couples intramolecular interactions to inhibition of catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src autoinhibition: let us count the ways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyr527 is phosphorylated in pp60c-src: implications for regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of Src family kinases in mouse embryos that lack Csk.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitory tyrosine protein kinase p50csk is associated with protein-tyrosine phosphatase PTP-PEST in hemopoietic and non-hemopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the csk gene suppresses tumor metastasis in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phosphotyrosine displacement mechanism for activation of Src by PTPalpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between the PDGF receptor and members of the src family of tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2- and SH3-mediated interactions between focal adhesion kinase and Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of c-SRC activity and function by the adapter protein CAS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p60c-src with endosomal membranes in mammalian fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and translocation of c-Src to the cytoskeleton by both platelet-derived growth factor and epidermal growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paxillin
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin-mediated degradation of active Src tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin-dependent degradation of active Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of the Catalytic Activity of the Src Family Tyrosine Kinase Hck by Autophosphorylation at a Novel Site in the Unique Domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide controls src kinase activity through a sulfhydryl group modification-mediated Tyr-527-independent and Tyr-416-linked mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the v-Src oncoprotein in fibroblasts disrupts normal regulation of the CDK inhibitor p27 and inhibits quiescence.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through focal adhesion kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine residues 239 and 240 of Shc are phosphatidylinositol 4,5-bisphosphate-dependent phosphorylation sites by c-Src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of both apoptosis and cell survival by the v-Src oncoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The selective isolation of temperature-sensitive mutants of Rous sarcoma virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of epithelial cell-matrix interactions induces apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src family tyrosine kinases and growth factor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple roles for Src in a PDGF-stimulated cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered phosphorylation and activation of pp60c-src during fibroblast mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src family kinases are required for integrin but not PDGFR signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caveolin, a protein component of caveolae membrane coats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal Growth Factor-stimulated Tyrosine Phosphorylation of Caveolin-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of caveolin and caveolae in oncogenically transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA genetics of breast cancer: maspin as paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A target for Src in mitosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a novel cytoskeleton-associated pp60src substrate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impairment of mobility in endodermal cells by FAK deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of focal adhesion kinase gene and invasive cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of focal adhesion kinase by different proteases during SRC-regulated transformation and apoptosis. Distinct roles for calpain and caspases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell motility by mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases control polarity, protrusion, and adhesion during cell movement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative study of hepatocyte growth factor/scatter factor and keratinocyte growth factor effects on human keratinocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of RhoA by p120 catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p120 catenin regulates the actin cytoskeleton via Rho family GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The crossroads between cell-cell adhesion and motility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Src phosphorylation sites in the catenin p120ctn
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p120-catenin expression in human colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A causal role for E-cadherin in the transition from adenoma to carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E-cadherin germline mutations in familial gastric cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src and Ras are involved in separate pathways in epithelial cell scattering
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of c-Src tyrosine kinase in EGF-induced mitogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAK integrates growth-factor and integrin signals to promote cell migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transforming activity of activated G alpha 12.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two G protein oncogenes in human endocrine tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of the previously reported G protein oncogene (gip2) in ovarian granulosa cell tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation by Gi2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src tyrosine kinase is a novel direct effector of G proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and association of Stat3 with Src in v-Src-transformed cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of cell cycle regulation by v-Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900040-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-419X(02)00040-9
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
PubMed ID
12020799
1 reference
stated in
Europe PubMed Central
PubMed ID
12020799
retrieved
30 July 2017
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