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The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton
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instance of
scholarly article
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
title
The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton
(English)
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
main subject
cytoskeleton
0 references
author name string
P A Randazzo
series ordinal
1
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
J Andrade
series ordinal
2
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
K Miura
series ordinal
3
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
M T Brown
series ordinal
4
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
Y Q Long
series ordinal
5
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
S Stauffer
series ordinal
6
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
P Roller
series ordinal
7
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
J A Cooper
series ordinal
8
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
language of work or name
English
0 references
publication date
1 April 2000
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stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
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Q5412157
PubMed ID
10725410
retrieved
9 August 2017
volume
97
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stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
page(s)
4011-4016
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stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
issue
8
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
cites work
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation
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ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting
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12 July 2018
ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex
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A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins
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12 July 2018
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling
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EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization
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12 July 2018
GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitro
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Effectors for the Rho GTPases
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ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements
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12 July 2018
Identification of a new Pyk2 target protein with Arf-GAP activity
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ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts
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12 July 2018
Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis
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beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
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12 July 2018
ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO.
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PubMed Central
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12 July 2018
ARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control of Golgi structure and function
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
GTPase-activating proteins: helping hands to complement an active site.
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PubMed Central
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12 July 2018
A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
A requirement for ARF6 in Fcgamma receptor-mediated phagocytosis in macrophages
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PubMed Central
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12 July 2018
Localization of endogenous ARF6 to sites of cortical actin rearrangement and involvement of ARF6 in cell spreading
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13
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PubMed Central
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12 July 2018
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
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12 July 2018
The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate
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PubMed Central
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12 July 2018
ARF6 targets recycling vesicles to the plasma membrane: insights from an ultrastructural investigation
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PubMed Central
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12 July 2018
Cellular functions regulated by Src family kinases
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PubMed Central
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12 July 2018
Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate
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PubMed Central
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12 July 2018
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
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PubMed Central
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12 July 2018
A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Getting membrane flow and the cytoskeleton to cooperate in moving cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Regulation, substrates and functions of src
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Actin-based cell motility and cell locomotion
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Cell migration: a physically integrated molecular process
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PubMed Central
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12 July 2018
Cell adhesion: the molecular basis of tissue architecture and morphogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
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12 July 2018
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
12 July 2018
Molecules in the ARF orbit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
25 September 2018
Cell migration: regulation of force on extracellular-matrix-integrin complexes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
25 September 2018
ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
25 September 2018
GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipids.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18133
retrieved
25 September 2018
Phospholipase D: a downstream effector of ARF in granulocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.070552297
retrieved
21 January 2018
ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.070552297
retrieved
21 January 2018
Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric site
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Focal adhesion assembly
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activation of the phosphatidylinositol cycle in spreading cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
ARF: a key regulatory switch in membrane traffic and organelle structure
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Preparation of recombinant ADP-ribosylation factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activation of phospholipase D and phosphatidylinositol 4-phosphate 5-kinase in HL60 membranes is mediated by endogenous Arf but not Rho
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
ADP-ribosylation factor proteins mediate agonist-induced activation of phospholipase D
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10725410
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.070552297
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
ADS bibcode
2000PNAS...97.4011R
0 references
PMCID
18133
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
PubMed ID
10725410
1 reference
stated in
Q5412157
PubMed ID
10725410
retrieved
9 August 2017
ResearchGate publication ID
12591342
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