(Q39901137)

15 September 2017

Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes (English)

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15 September 2017

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1

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15 September 2017

6

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15 September 2017

Aldo Dobrina

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Maria Carmela Cerra

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Maria Carmela Cerra

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5

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author name string

Elisabetta Filice

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2

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PubMed ID

19111553

15 September 2017

Daniela Pellegrino

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3

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15 September 2017

10 December 2008

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Journal of Molecular and Cellular Cardiology

15 September 2017

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15 September 2017

46

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15 September 2017

352-359

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15 September 2017

3

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A novel potent vasoconstrictor peptide produced by vascular endothelial cells

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Historical review: Endothelin

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The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?

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Endothelin receptor antagonists

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Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats

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Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension

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All in the CCN family: essential matricellular signaling modulators emerge from the bunker

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Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

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CCN proteins: multifunctional signalling regulators

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Connective tissue growth factor induces cardiac hypertrophy through Akt signaling

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Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis.

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Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats

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Phenylephrine and endothelin-1 upregulate connective tissue growth factor in neonatal rat cardiac myocytes

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Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis

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Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells.

7 January 2021

1 reference

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Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

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Therapeutic potential of the epidermal growth factor receptor transactivation in hypertension: a convergent signaling pathway of vascular tone, oxidative stress, and hypertrophic growth downstream of vasoactive G-protein-coupled receptors?

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HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

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Recombinant N-terminal fragments of chromogranin-A modulate cardiac function of the Langendorff-perfused rat heart

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Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition.

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Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation

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Differential phosphorylation of c-Jun and JunD in response to the epidermal growth factor is determined by the structure of MAPK targeting sequences

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A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.

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Heparin binding EGF is necessary for vasospastic response to endothelin.

7 January 2021

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The EGF receptor as central transducer of heterologous signalling systems

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EGF receptor transactivation mediated by the proteolytic production of EGF-like agonists

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Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.

7 January 2021

1 reference

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

7 January 2021

1 reference

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Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways.

7 January 2021

1 reference

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Selective Involvement of p130Cas/Crk/Pyk2/c-Src in Endothelin-1-Induced JNK Activation

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Role of EGF Receptor and Pyk2 in endothelin-1-induced ERK activation in rat cardiomyocytes

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The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

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G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells

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Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites

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Endothelin signalling in the cardiac myocyte and its pathophysiological relevance

7 January 2021

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Upregulation of decorin by FXR in vascular smooth muscle cells

7 January 2021

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Regulation of cardiac hypertrophy by intracellular signalling pathways

7 January 2021

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CTGF expression is induced by TGF- beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis

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Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways

7 January 2021

1 reference

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Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes

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Increased expression of connective tissue growth factor in the infarct zone of experimentally induced myocardial infarction in rats

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

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Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin

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Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung

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Decorin overexpression reduces atherosclerosis development in apolipoprotein E-deficient mice

7 January 2021

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Effects of endothelins on collagen turnover in cardiac fibroblasts

7 January 2021

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Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia

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Endothelin-mediated remodeling in aortas of diabetic rats

7 January 2021

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Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways

7 January 2021

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Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway

7 January 2021

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Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation

7 January 2021

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Dominant negative mutant of c-Jun inhibits cardiomyocyte hypertrophy induced by endothelin 1 and phenylephrine

7 January 2021

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10.1016/J.YJMCC.2008.11.017

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

1 reference

PubMed ID

19111553