(Q39905823)

English

Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration.

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6714047&resulttype=core&format=json

12 May 2020

apoptotic process

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1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

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author name string

R Merline

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6714047&resulttype=core&format=json

12 May 2020

S Lazaroski

2

1 reference

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12 May 2020

A Babelova

3

1 reference

Europe PubMed Central

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12 May 2020

W Tsalastra-Greul

4

1 reference

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12 May 2020

J Pfeilschifter

5

1 reference

Europe PubMed Central

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12 May 2020

K D Schluter

6

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12 May 2020

A Gunther

7

1 reference

Europe PubMed Central

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12 May 2020

R V Iozzo

8

1 reference

Europe PubMed Central

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12 May 2020

R M Schaefer

9

1 reference

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12 May 2020

L Schaefer

10

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12 May 2020

publication date

1 October 2009

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15 September 2017

Journal of Physiology and Pharmacology

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12 May 2020

60 Suppl 4

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12 May 2020

5-13

1 reference

Europe PubMed Central

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12 May 2020

Influence of decorin expression on transforming growth factor-beta-mediated collagen gel retraction and biglycan induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hypertrophic effect of transforming growth factor-beta is reduced in the absence of cyclin-dependent kinase-inhibitors p21 and p27

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of biglycan gene expression by transforming growth factor-beta requires MKK6-p38 mitogen-activated protein Kinase signaling downstream of Smad signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erk 1,2 phosphorylates p27(Kip1): Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin prevents metastatic spreading of breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin, a novel player in the insulin-like growth factor system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The podocyte's response to injury: role in proteinuria and glomerulosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors: emerging concepts in kidney disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms of proteinuria in diabetic nephropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the kidneys of patients with type II diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin deficiency enhances progressive nephropathy in diabetic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of inflammation in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced glycation end-products induce cell cycle arrest and hypertrophy in podocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteinuria in diabetic kidney disease: a mechanistic viewpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of decorin induces apoptosis and cell growth arrest in cultured rat mesangial cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An antimetastatic role for decorin in breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel regulatory mechanisms for the proteoglycans decorin and biglycan during muscle formation and muscular dystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin-mediated inhibition of proliferation and migration of the human trophoblast via different tyrosine kinase receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of transforming growth factor-beta by the proteoglycan decorin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural-functional relationships in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of glutamate in a central leucine-rich repeat of decorin for interaction with type I collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin, biglycan and their endocytosis receptor in rat renal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20083846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6714047&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6714047&resulttype=core&format=json

12 May 2020

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