(Q39906264)

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Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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author name string

Adelaide M Carothers

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Jennifer S Davids

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Beatrice C Damas

3

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Monica M Bertagnolli

4

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Europe PubMed Central

PMC publication ID

15 September 2017

language of work or name

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publication date

18 May 2010

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Europe PubMed Central

PMC publication ID

15 September 2017

Cancer Research

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Europe PubMed Central

PMC publication ID

15 September 2017

70

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Europe PubMed Central

PMC publication ID

15 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

4433-4442

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3242378/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Chronic cyclooxygenase-2 inhibition promotes myofibroblast-associated intestinal fibrosis

1 reference

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Potential pharmacological control of the NF-κB pathway

1 reference

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1 reference

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Opposing functions of IKKbeta during acute and chronic intestinal inflammation

1 reference

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Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

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Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation

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NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

1 reference

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Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

1 reference

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Chemoprevention of colorectal cancer with cyclooxygenase-2 inhibitors: two steps forward, one step back

1 reference

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Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

1 reference

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Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR.

1 reference

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Celecoxib treatment alters the gene expression profile of normal colonic mucosa

1 reference

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Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

1 reference

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Nuclear factor-kappaB in cancer development and progression

1 reference

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Connecting COX-2 and Wnt in cancer

1 reference

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

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Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.

1 reference

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15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers

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Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.

1 reference

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Interleukin-1beta-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells

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1 reference

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Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes

1 reference

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1 reference

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1 reference

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Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice.

1 reference

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1 reference

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1 reference

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Changes in antitumor response in C57BL/6J-Min/+ mice during long-term administration of a selective cyclooxygenase-2 inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484034

12 December 2020

based on heuristic

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Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484034

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Bacterial infection promotes colon tumorigenesis in Apc(Min/+) mice

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https://pubmed.ncbi.nlm.nih.gov/20484034

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https://pubmed.ncbi.nlm.nih.gov/20484034

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based on heuristic

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Identifiers

10.1158/0008-5472.CAN-09-4289

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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