(Q42832730)

English

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

scientific article published on 26 October 2009

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scholarly article

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11 February 2020

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions (English)

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11 February 2020

extracellular matrix

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7

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11 February 2020

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Ulf Anderegg

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11 February 2020

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Meinhard Schiller

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11 February 2020

Sylviane Dennler

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11 February 2020

Agatha Kokot

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11 February 2020

Jan C Simon

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11 February 2020

Thomas A Luger

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11 February 2020

Markus Böhm

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11 February 2020

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26 October 2009

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11 February 2020

Journal of Biological Chemistry

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11 February 2020

285

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11 February 2020

1

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11 February 2020

409-421

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11 February 2020

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11 June 2022

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cAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts

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The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP.

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Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis

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Cell migration: Rho GTPases lead the way

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Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

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Control of connective tissue gene expression by TGF beta: role of Smad proteins in fibrosis.

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Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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27 May 2018

Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation

1 reference

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Inhibition of PKA blocks fibroblast migration in response to growth factors.

1 reference

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Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung

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How cells read TGF-beta signals

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Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases

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Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells

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Transcriptional regulation of the transforming growth factor-beta -inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members.

1 reference

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27 May 2018

SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

1 reference

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Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300.

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

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27 May 2018

Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta

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Transcriptional regulation by cyclic AMP.

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CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter

1 reference

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1 reference

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alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?

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12 December 2020

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Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.038620

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858184%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858184%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858184%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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