(Q44679407)

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Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.

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21 December 2019

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism (English)

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21 December 2019

Franck Verrecchia

2

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21 December 2019

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21 December 2019

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Meinhard Schiller

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21 December 2019

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21 December 2019

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21 December 2019

22

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21 December 2019

55

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21 December 2019

8881-8890

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21 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206871

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SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

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Human p300 protein is a coactivator for the transcription factor MyoD

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Phosphorylated CREB binds specifically to the nuclear protein CBP

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP

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The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

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Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators

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Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

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TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

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7 January 2021

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Nuclear protein CBP is a coactivator for the transcription factor CREB

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Transcriptional control by the TGF-beta/Smad signaling system

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7 January 2021

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Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor.

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7 January 2021

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Transcriptional regulation by cyclic AMP.

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7 January 2021

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Physical and functional interaction of SMADs and p300/CBP

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7 January 2021

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TGF-beta and cancer.

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Coupling gene expression to cAMP signalling: role of CREB and CREM.

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TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein

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Identifiers

10.1038/SJ.ONC.1206871

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21 December 2019

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