(Q40690939)

English

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

scientific article published on 7 November 2002

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Erwin F. Wagner

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Franck Verrecchia

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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Charlotte Tacheau

2

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Europe PubMed Central

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14 December 2019

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7 November 2002

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Europe PubMed Central

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14 December 2019

Journal of Biological Chemistry

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14 December 2019

278

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

3

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14 December 2019

1585-1593

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

TGF-beta: regulation of extracellular matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Cytokine regulation of metalloproteinase gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Transcriptional interactions of transforming growth-factor-beta with pro-inflammatory cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-beta in fibroblasts and keratinocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

c-Jun inhibits transforming growth factor beta-mediated transcription by repressing Smad3 transcriptional activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Smads bind directly to the Jun family of AP-1 transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Human Smad3 and Smad4 are sequence-specific transcription activators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Transformation by ras modifies AP1 composition and activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

JunB can substitute for Jun in mouse development and cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor beta-mediated signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206927200

21 January 2018

Identifiers

10.1074/JBC.M206927200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

release_mflfc6fbuzdxdaw7uefgyttxje

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https://api.fatcat.wiki/v0/release/mflfc6fbuzdxdaw7uefgyttxje

24 November 2022

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12426318%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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