(Q39914745)

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Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production

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Europe PubMed Central

PubMed publication ID

15 September 2017

Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production (English)

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Europe PubMed Central

PubMed publication ID

15 September 2017

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Chien-Cheng Chiang

1

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Europe PubMed Central

PubMed publication ID

15 September 2017

Shiu-Mei Wang

2

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Europe PubMed Central

PubMed publication ID

15 September 2017

Ying-Tzu Tseng

3

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Europe PubMed Central

PubMed publication ID

15 September 2017

Kuo-Jung Huang

4

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Europe PubMed Central

PubMed publication ID

15 September 2017

Chin-Tien Wang

5

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Europe PubMed Central

PubMed publication ID

15 September 2017

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publication date

20 November 2008

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Europe PubMed Central

PubMed publication ID

15 September 2017

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Europe PubMed Central

PubMed publication ID

15 September 2017

383

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Europe PubMed Central

PubMed publication ID

15 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

261-270

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy

1 reference

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7 January 2021

Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.

1 reference

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7 January 2021

Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

1 reference

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7 January 2021

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

1 reference

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7 January 2021

Pleiotropic mutations in the HIV-1 matrix protein that affect diverse steps in replication

1 reference

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7 January 2021

Incorporation of pol into human immunodeficiency virus type 1 Gag virus-like particles occurs independently of the upstream Gag domain in Gag-pol

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Generation of infectious virus particles by transient co-expression of human immunodeficiency virus type 1 gag mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

The virus-associated human immunodeficiency virus type 1 Gag-Pol carrying an active protease domain in the matrix region is severely defective both in autoprocessing and in trans processing of gag particles

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

A domain directly C-terminal to the major homology region of human immunodeficiency type 1 capsid protein plays a crucial role in directing both virus assembly and incorporation of Gag-Pol

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Coding sequences upstream of the human immunodeficiency virus type 1 reverse transcriptase domain in Gag-Pol are not essential for incorporation of the Pr160(gag-pol) into virus particles

1 reference

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Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.

1 reference

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7 January 2021

Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure

1 reference

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7 January 2021

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

1 reference

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7 January 2021

Folding of the multidomain human immunodeficiency virus type-I integrase

1 reference

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Rapid localization of Gag/GagPol complexes to detergent-resistant membrane during the assembly of human immunodeficiency virus type 1.

1 reference

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7 January 2021

Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants

1 reference

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7 January 2021

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Characterization of human immunodeficiency virus type 1 Pr160 gag-pol mutants with truncations downstream of the protease domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Incorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particles

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Analysis of human immunodeficiency virus type 1 reverse transcriptase subunit structure/function in the context of infectious virions and human target cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Genotypic predictors of human immunodeficiency virus type 1 drug resistance

1 reference

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7 January 2021

Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Effects of efavirenz binding on the subunit equilibria of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Assembly and processing of human immunodeficiency virus Gag mutants containing a partial replacement of the matrix domain by the viral protease domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

Association of murine leukemia virus pol with virions, independent of Gag-Pol expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

based on heuristic

inferred from DOI database lookup

Incorporation of Pr160(gag-pol) into virus particles requires the presence of both the major homology region and adjacent C-terminal capsid sequences within the Gag-Pol polyprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

based on heuristic

inferred from DOI database lookup

The human foamy virus pol gene is expressed as a Pro-Pol polyprotein and not as a Gag-Pol fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.10.027

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIROL.2008.10.027

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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