(Q39934413)

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Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.

scientific article published on 9 March 2016

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26960398%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets (English)

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10 March 2020

large cell neuroendocrine carcinoma of the lung

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14

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10 March 2020

19

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10 March 2020

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Natasha Rekhtman

1

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10 March 2020

Maria C Pietanza

2

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10 March 2020

Matthew D Hellmann

3

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10 March 2020

Jarushka Naidoo

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10 March 2020

Arshi Arora

5

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10 March 2020

Helen Won

6

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10 March 2020

Darragh F Halpenny

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10 March 2020

Hangjun Wang

8

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10 March 2020

Shaozhou K Tian

9

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10 March 2020

Anya M Litvak

10

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10 March 2020

Paul K Paik

11

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10 March 2020

Alexander E Drilon

12

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10 March 2020

Nicholas Socci

13

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10 March 2020

Ronglai Shen

15

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10 March 2020

Michael F Berger

16

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10 March 2020

Andre L Moreira

17

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10 March 2020

William D Travis

18

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10 March 2020

Marc Ladanyi

20

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10 March 2020

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9 March 2016

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10 March 2020

Clinical Cancer Research

1 reference

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10 March 2020

22

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10 March 2020

14

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10 March 2020

3618-3629

1 reference

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10 March 2020

Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Comprehensive genomic profiles of small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

The high-grade (WHO G3) pancreatic neuroendocrine tumor category is morphologically and biologically heterogenous and includes both well differentiated and poorly differentiated neoplasms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Tyrosine Kinase Inhibitors in EGFR-Mutated Large-Cell Neuroendocrine Carcinoma of the Lung? A Case Report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Comprehensive molecular profiling of lung adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

A genomics-based classification of human lung tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Distinct profile of driver mutations and clinical features in immunomarker-defined subsets of pulmonary large-cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Neoadjuvant and adjuvant chemotherapy in resected pulmonary large cell neuroendocrine carcinomas: a single institution experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Neuroendocrine tumors of the lung: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

LKB1 modulates lung cancer differentiation and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Pulmonary large cell neuroendocrine carcinoma: its place in the spectrum of pulmonary carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4995776

22 September 2017

Rb family proteins differentially regulate distinct cell lineages during epithelial development

1 reference

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22 September 2017

Achaete-scute homolog-1 and Notch in lung neuroendocrine development and cancer

1 reference

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22 September 2017

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

1 reference

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22 September 2017

Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases

1 reference

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22 September 2017

Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.

1 reference

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17 June 2018

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Large-cell neuroendocrine carcinoma of the lung harboring EGFR mutation and responding to gefitinib.

1 reference

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20 August 2018

Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung

1 reference

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20 August 2018

Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung

1 reference

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20 August 2018

Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome.

1 reference

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20 August 2018

Should Large Cell Neuroendocrine Lung Carcinoma be Classified and Treated as a Small Cell Lung Cancer or with Other Large Cell Carcinomas?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical endocrine tumors of the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A case of large-cell neuroendocrine carcinoma harboring an EML4-ALK rearrangement with resistance to the ALK inhibitor crizotinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Markers Help Characterize Neuroendocrine Lung Tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bringing the genomic landscape of small-cell lung cancer into focus

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reproducibility of neuroendocrine lung tumor classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/26960398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-15-2946

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26960398%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26960398%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26960398%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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