(Q36042596)

11 August 2017

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2. (English)

1 reference

11 August 2017

0 references

1 reference

1

1 reference

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5 June 2020

Charles Rudin

7

1 reference

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5 June 2020

author name string

E E Gardner

2

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5 June 2020

N Connis

3

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5 June 2020

A L Moreira

4

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5 June 2020

E de Stanchina

5

1 reference

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5 June 2020

C L Hann

6

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5 June 2020

language of work or name

English

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publication date

9 March 2015

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11 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746006%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

34

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5 June 2020

issue

48

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5 June 2020

page(s)

5869-5878

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https://scigraph.springernature.com/pub.10.1038/onc.2015.38

5 June 2020

exact match

0 references

cites work

EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer.

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Rapamycin rescues ABT-737 efficacy in small cell lung cancer

2 October 2017

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Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

2 October 2017

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A genomics-based classification of human lung tumors

2 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Charting a dynamic DNA methylation landscape of the human genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

2 October 2017

Cancer genome landscapes

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Dynamic DNA methylation across diverse human cell lines and tissues

2 October 2017

1 reference

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Comprehensive molecular portraits of human breast tumours

2 October 2017

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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

2 October 2017

1 reference

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Comprehensive genomic characterization of squamous cell lung cancers

2 October 2017

1 reference

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

2 October 2017

1 reference

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Comprehensive molecular characterization of human colon and rectal cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

2 October 2017

1 reference

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Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

2 October 2017

Cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

The role of EZH2 in tumour progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

2 October 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Fast, hungry and unstable: finding the Achilles' heel of small-cell lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Molecular genetics of small cell lung carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Increased methylation variation in epigenetic domains across cancer types

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Establishment and identification of small cell lung cancer cell lines having classic and variant features.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Methylation subtypes and large-scale epigenetic alterations in gastric cancer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564363

Multiple-laboratory comparison of microarray platforms

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2015.38

VP16-213 combined with cis-platinum (CDDP) in the treatment of small cell carcinoma of the lung (SCLC)

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2015.38

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2015.38

31 March 2020

Identifiers

DOI

10.1038/ONC.2015.38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746006%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746006%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

25746006

1 reference