(Q36240860)

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MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

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Europe PubMed Central

PMC publication ID

13 August 2017

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status (English)

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Europe PubMed Central

PMC publication ID

13 August 2017

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corrigendum / erratum

Erratum to: MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and

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Jacqueline Bloch

4

object named as

Jocelyne Bloch

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Europe PubMed Central

PMC publication ID

13 August 2017

8

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Michael Weller

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Europe PubMed Central

13 August 2017

PMC publication ID

Pierre-Yves Dietrich

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object named as

Pierre-Yves Dietrich

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13 August 2017

author name string

Pierre Bady

1

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13 August 2017

Davide Sciuscio

2

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13 August 2017

Annie-Claire Diserens

3

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13 August 2017

Martin J van den Bent

5

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Europe PubMed Central

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13 August 2017

Christine Marosi

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13 August 2017

Luigi Mariani

9

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13 August 2017

Frank L Heppner

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13 August 2017

David R Mcdonald

11

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Europe PubMed Central

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13 August 2017

Denis Lacombe

12

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Europe PubMed Central

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13 August 2017

Roger Stupp

13

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Europe PubMed Central

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13 August 2017

Mauro Delorenzi

14

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Europe PubMed Central

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13 August 2017

Monika E Hegi

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13 August 2017

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19 July 2012

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Europe PubMed Central

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13 August 2017

Acta Neuropathologica

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13 August 2017

124

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13 August 2017

4

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13 August 2017

547-560

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Europe PubMed Central

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13 August 2017

Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial

1 reference

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Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

1 reference

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

1 reference

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Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial

1 reference

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1 reference

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A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951.

1 reference

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Genome-scale analysis of aberrant DNA methylation in colorectal cancer

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1 reference

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A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.

1 reference

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1 reference

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DNA methylation in glioblastoma: impact on gene expression and clinical outcome

1 reference

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

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Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

1 reference

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

1 reference

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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1 October 2017

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

1 reference

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1 October 2017

MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

1 reference

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1 October 2017

Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

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1 October 2017

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma

1 reference

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1 October 2017

Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

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1 reference

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Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

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Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer

1 reference

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1 October 2017

Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

CpG island methylator phenotype in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

1 October 2017

Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene

1 reference

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1 October 2017

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

22 September 2018

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1 reference

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22 September 2018

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.

1 reference

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22 September 2018

Extent and patterns of MGMT promoter methylation in glioblastoma- and respective glioblastoma-derived spheres.

1 reference

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22 September 2018

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444709

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1 reference

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22 September 2018

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22810491

12 December 2020

based on heuristic

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CpG island methylator phenotype in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22810491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00401-012-1016-2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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