(Q37649471)

21 August 2017

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title

MGMT promoter methylation in malignant gliomas: ready for personalized medicine? (English)

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21 August 2017

personalized medicine

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1

Michael Weller

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21 August 2017

6

Wolfgang Wick

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21 August 2017

3

Guido Reifenberger

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21 August 2017

4

Alba A Brandes

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PubMed ID

19997073

21 August 2017

Martin J van den Bent

series ordinal

5

object named as

Martin J van den Bent

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21 August 2017

7

Monika E Hegi

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21 August 2017

2

Roger Stupp

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PubMed ID

19997073

21 August 2017

language of work or name

English

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publication date

8 December 2009

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21 August 2017

Nature Reviews Neurology

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21 August 2017

6

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21 August 2017

39-51

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21 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrneurol.2009.197

21 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma

31 March 2020

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31 March 2020

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31 March 2020

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Hypermethylation of the DNA repair gene MGMT: association with TP53 G:C to A:T transitions in a series of 469 nervous system tumors

31 March 2020

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Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene

31 March 2020

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Phenotype versus genotype correlation in oligodendrogliomas and low-grade diffuse astrocytomas

31 March 2020

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Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas

31 March 2020

1 reference

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Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)

31 March 2020

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Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors.

31 March 2020

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Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas

31 March 2020

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O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course

31 March 2020

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O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme

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12 December 2020

Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent

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Repair of O(6)-alkylguanine by alkyltransferases

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Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine

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12 December 2020

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

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12 December 2020

Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas

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12 December 2020

MGMT immunohistochemical expression and promoter methylation in human glioblastoma

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12 December 2020

In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene

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12 December 2020

O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications

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12 December 2020

O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy.

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12 December 2020

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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12 December 2020

10.1038/NRNEUROL.2009.197

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19997073