(Q39938289)

English

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.

scientific article published on October 2008

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL. (English)

1 reference

Europe PubMed Central

15 September 2017

Michael L Dustin

6

1 reference

Europe PubMed Central

15 September 2017

author name string

Allison M Beal

1

1 reference

Europe PubMed Central

15 September 2017

Nadia Anikeeva

2

1 reference

Europe PubMed Central

15 September 2017

Rajat Varma

3

1 reference

Europe PubMed Central

15 September 2017

Thomas O Cameron

4

1 reference

Europe PubMed Central

15 September 2017

Philip J Norris

5

1 reference

Europe PubMed Central

15 September 2017

Yuri Sykulev

7

1 reference

Europe PubMed Central

15 September 2017

language of work or name

0 references

publication date

1 October 2008

1 reference

Europe PubMed Central

15 September 2017

Journal of Immunology

1 reference

Europe PubMed Central

15 September 2017

181

1 reference

Europe PubMed Central

15 September 2017

7

1 reference

Europe PubMed Central

15 September 2017

4815-4824

1 reference

Europe PubMed Central

15 September 2017

T-cell activation through immunological synapses and kinapses

1 reference

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In vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells.

1 reference

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22 September 2017

Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Synapses: sites of cell recognition, adhesion, and functional specification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Expression and function of synaptotagmin VII in CTLs

1 reference

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22 September 2017

The role of actomyosin and the microtubular network in both the immunological synapse and T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role

1 reference

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22 September 2017

Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response

1 reference

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22 September 2017

Recruitment of dynein to the Jurkat immunological synapse

1 reference

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22 September 2017

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

1 reference

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22 September 2017

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses.

1 reference

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22 September 2017

Immunological synapse and microclusters: the site for recognition and activation of T cells

1 reference

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22 September 2017

Virus-specific CD4+ T cells: ready for direct attack

1 reference

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22 September 2017

Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Cytotoxic T lymphocytes form an antigen-independent ring junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Neural and immunological synaptic relations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

T cell receptor signaling precedes immunological synapse formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Mechanism and biological significance of CD4-mediated cytotoxicity

1 reference

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22 September 2017

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation

1 reference

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22 September 2017

Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

22 September 2017

Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

25 September 2017

The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

17 June 2018

The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

17 June 2018

Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

17 June 2018

Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

17 June 2018

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

17 June 2018

Centrosome polarization delivers secretory granules to the immunological synapse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

T cells use two directionally distinct pathways for cytokine secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

T cell killing does not require the formation of a stable mature immunological synapse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

The immunological synapse of CTL contains a secretory domain and membrane bridges.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

20 August 2018

Multifocal structure of the T cell - dendritic cell synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

1 October 2018

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

2 December 2018

Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

2 December 2018

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748977

2 December 2018

Characterization of CD4(+) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct molecular mechanisms account for the specificity of two different T-cell receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine esterase in cytolytic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of potent and selective PKC-theta inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.181.7.4815

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

ResearchGate publication ID

0 references

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