(Q39938427)

15 September 2017

Heparan sulfate regulates ADAM12 through a molecular switch mechanism (English)

1 reference

15 September 2017

8

Ulla M Wewer

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author name string

Hans Peter Sørensen

1

1 reference

15 September 2017

Romain R Vivès

2

1 reference

15 September 2017

Christina Manetopoulos

3

1 reference

15 September 2017

Reidar Albrechtsen

4

1 reference

15 September 2017

Magnus C Lydolph

5

1 reference

15 September 2017

Jonas Jacobsen

6

1 reference

15 September 2017

John R Couchman

7

1 reference

15 September 2017

Ulla M Wewer

8

1 reference

15 September 2017

language of work or name

English

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publication date

17 September 2008

1 reference

Journal of Biological Chemistry

15 September 2017

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15 September 2017

283

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15 September 2017

31920-31932

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15 September 2017

46

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Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions

15 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Syndecans: proteoglycan regulators of cell-surface microdomains?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Structural insights into biological roles of protein-glycosaminoglycan interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Interactions between heparan sulfate and proteins: the concept of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Roles of heparan-sulphate glycosaminoglycans in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparin, heparan sulfate and heparanase in cancer: remedy for metastasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Factors regulating trophoblast invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Cellular roles of ADAM12 in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

A role for ADAM12 in breast tumor progression and stromal cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Human ADAM 12 (meltrin alpha) is an active metalloprotease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Intracellular maturation of the mouse metalloprotease disintegrin MDC15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Human ADAM33: protein maturation and localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Chaperone-like properties of the prodomain of TNFalpha-converting enzyme (TACE) and the functional role of its cysteine switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Generation of monoclonal antibodies for the assessment of protein purification by recombinant ribosomal coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Catalytic properties of ADAM12 and its domain deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparan sulfate proteoglycan mediates the selective attachment and internalization of serotype 3 human adenovirus dodecahedron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

A novel strategy for defining critical amino acid residues involved in protein/glycosaminoglycan interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Structure-based virtual screening and biological evaluation of potent and selective ADAM12 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparan sulfate proteoglycans as adhesive and anti-invasive molecules. Syndecans and glypican have distinct functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Specific sequence elements are required for the expression of functional tumor necrosis factor-alpha-converting enzyme (TACE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM12: a novel first-trimester maternal serum marker for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Insulin-like growth factor binding protein proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Human placental trophoblasts secrete a disintegrin metalloproteinase very similar to the insulin-like growth factor binding protein-3 protease in human pregnancy serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs) -3, -5, and -6 inhibit IGFBP-4 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Osteoarthritis, genetic and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

The anticoagulant activation of antithrombin by heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Pentasaccharide enhances the inactivation of factor Xa by antithrombin by promoting the assembly of a Michaelis-type intermediate complex. Demonstration by rapid kinetic, surface plasmon resonance, and competitive binding studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Characterization of glycosaminoglycan-binding domains present in insulin-like growth factor-binding protein-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Molecular interactions in the insulin-like growth factor (IGF) axis: a surface plasmon resonance (SPR) based biosensor study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Proteoglycans: structures and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Is human placenta proteoglycan remodeling involved in pre-eclampsia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Epidermal growth factor receptor (EGFR) signaling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Advances in male contraception

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

Molecular Profiling of ADAM12 in Human Bladder Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM12 Is a Four-leafed Clover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

ADAM12-S Stimulates Bone Growth in Transgenic Mice by Modulating Chondrocyte Proliferation and Maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804113200

21 January 2018

Identifiers

DOI

10.1074/JBC.M804113200

1 reference

15 September 2017

1 reference