(Q39946656)

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Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.

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Europe PubMed Central

PubMed publication ID

15 September 2017

Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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A Novials

2

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F Reimann

3

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author name string

S Casas

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

R Gomis

4

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

F M Gribble

5

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

publication date

28 August 2008

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

51

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

2252-2262

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal studies on the development of diabetes in individual Macaca nigra

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pore formation by the cytotoxic islet amyloid peptide amylin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NCX1 Na/Ca exchanger splice variants in pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a prion protein fragment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid polypeptide (IAPP) and pro-IAPP immunoreactivity in human islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium orchestrates apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron Microscopic Observations on a Fibrous Component in Amyloid of Diverse Origins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Ca2+ in apoptosis evoked by human amylin in pancreatic islet beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid catalysis of diabetic amyloid assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pancreatic islet cells in insular amyloidosis in human diabetic and non-diabetic adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human type 2 diabetes: morphological evidence for abnormal beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine structure of islets of Langerhans in insular amyloidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18751967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-008-1111-Z

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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