(Q39956375)

15 September 2017

Pituitary tumor transforming gene 1 regulates Aurora kinase A activity (English)

1 reference

15 September 2017

Y Tong

1

1 reference

15 September 2017

A Ben-Shlomo

2

1 reference

15 September 2017

C Zhou

3

1 reference

15 September 2017

K Wawrowsky

4

1 reference

15 September 2017

S Melmed

5

1 reference

15 September 2017

language of work or name

English

0 references

publication date

28 July 2008

1 reference

15 September 2017

1 reference

15 September 2017

27

1 reference

15 September 2017

6385-6395

1 reference

15 September 2017

49

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2008.234

15 September 2017

0 references

cites work

A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

p53 stabilization can be uncoupled from its role in transcriptional activation by loss of PTTG1/securin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Proliferative potential after DNA damage and non-homologous end joining are affected by loss of securin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

A potential role for PTTG/securin in the developing human fetal brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor-transforming gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor transforming gene overexpression facilitates pituitary tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Functional interaction of Aurora-A and PP2A during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

The dual mechanism of separase regulation by securin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Mitotic activation of the kinase Aurora-A requires its binding partner Bora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

The important anti-apoptotic role and its regulation mechanism of PTTG1 in UV-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Mitotic kinases: the key to duplication, segregation, and cytokinesis errors, chromosomal instability, and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora kinases as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Activation of mitogen-activated protein kinase cascade regulates pituitary tumor-transforming gene transactivation function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Identification of c-myc as a down-stream target for pituitary tumor-transforming gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Separase Regulates INCENP-Aurora B Anaphase Spindle Function Through Cdc14

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Phosphorylation of serine 10 in histone H3, what for?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Evidence for cooperative transforming activity of the human pituitary tumor transforming gene and human T-cell leukemia virus type 1 Tax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora kinase inhibition downregulates NF-kappaB and sensitises tumour cells to chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Expression of PTTG and prc1 genes during telencephalic neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor-transforming gene: physiology and implications for tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

The mitotic spindle checkpoint is a critical determinant for topoisomerase-based chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Regulation of human separase by securin binding and autocleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor transforming gene (PTTG) transforming and transactivation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Identification of the auto-inhibitory domains of Aurora-A kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

A novel mechanism for activation of the protein kinase Aurora A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Expression of pituitary-tumour transforming gene in colorectal tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Inhibition of Aurora A in response to DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

PTTG mRNA expression in primary breast cancer: a prognostic marker for lymph node invasion and tumor recurrence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.234

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.234

1 reference

15 September 2017

1 reference