(Q63241575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

7

1 reference

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4 January 2020

author name string

D Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

T Shimizu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

N Araki

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

T Hirota

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

M Yoshie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

K Ogawa

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

M Takeya

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

H Saya

9

1 reference

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4 January 2020

language of work or name

English

0 references

publication date

31 March 2008

1 reference

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4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

31

1 reference

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4 January 2020

page(s)

4305-4314

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18372918%20AND%20SRC:MED&resulttype=core&format=json

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

4 January 2020

cites work

1 reference

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Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

31 March 2020

1 reference

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

31 March 2020

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Tumor suppressors and oncogenes in cellular senescence.

31 March 2020

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Genetic instability and darwinian selection in tumours

31 March 2020

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Oxidative DNA damage and senescence of human diploid fibroblast cells.

31 March 2020

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Tumour biology: senescence in premalignant tumours

31 March 2020

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Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

31 March 2020

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

31 March 2020

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Oncogenic ras and p53 cooperate to induce cellular senescence

31 March 2020

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

31 March 2020

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Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein

31 March 2020

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Aurora kinases, aneuploidy and cancer, a coincidence or a real link?

31 March 2020

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31 March 2020

The Hallmarks of Cancer

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Regulation of cellular senescence by Rb2/p130.

31 March 2020

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Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

31 March 2020

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Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends

31 March 2020

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Overexpression and amplification of Aurora-A in hepatocellular carcinoma

31 March 2020

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Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

31 March 2020

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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

31 March 2020

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CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function

31 March 2020

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Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

31 March 2020

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p53, the cellular gatekeeper for growth and division

31 March 2020

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Genes involved in senescence and immortalization

31 March 2020

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Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

31 March 2020

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Aurora-A - a guardian of poles

31 March 2020

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

31 March 2020

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

31 March 2020

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Mitotic kinases as regulators of cell division and its checkpoints

31 March 2020

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Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

31 March 2020

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The antioxidant function of the p53 tumor suppressor

31 March 2020

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Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

31 March 2020

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A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

31 March 2020

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31 March 2020

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

31 March 2020

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

31 March 2020

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

31 March 2020

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Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

31 March 2020

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p53 and E2F-1 cooperate to mediate apoptosis

31 March 2020

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Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

31 March 2020

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

31 March 2020

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Senescence of human fibroblasts induced by oncogenic Raf.

31 March 2020

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