(Q39957446)

15 September 2017

title

Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells (English)

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15 September 2017

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Hatasu Kobayashi

1

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author name string

Shinji Oikawa

2

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15 September 2017

So Umemura

3

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15 September 2017

Iwao Hirosawa

4

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15 September 2017

Shosuke Kawanishi

5

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15 September 2017

language of work or name

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1 July 2008

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15 September 2017

published in

Free Radical Research

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15 September 2017

volume

42

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15 September 2017

issue

7

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15 September 2017

page(s)

651-660

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Toxin-induced models of Parkinson's disease

15 September 2017

cites work

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Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.

21 January 2018

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Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway

21 January 2018

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Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats

21 January 2018

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Aggravation of 6-hydroxydopamine-induced dopaminergic lesions in metallothionein-I and -II knock-out mouse brain

21 January 2018

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Roles of the metallothionein family of proteins in the central nervous system

21 January 2018

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The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification

21 January 2018

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p53 in neuronal apoptosis

21 January 2018

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p53-dependent cell death signaling in neurons

21 January 2018

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6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatum

21 January 2018

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Increased 8-OHdG levels in the urine, serum, and substantia nigra of hemiparkinsonian rats

21 January 2018

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Mechanism for manganese enhancement of dopamine-induced oxidative DNA damage and neuronal cell death.

21 January 2018

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Mechanism of DNA damage and apoptosis induced by tetrahydropapaveroline, a metabolite of dopamine

21 January 2018

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Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

21 January 2018

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Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis

21 January 2018

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Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

21 January 2018

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

21 January 2018

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Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus

21 January 2018

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Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

21 January 2018

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8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures

21 January 2018

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Formation of DNA adducts and oxidative base damage by copper mediated oxidation of dopamine and 6-hydroxydopamine

21 January 2018

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Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide.

21 January 2018

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Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms

21 January 2018

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Specificity of oxygen radical scavengers and assessment of free radical scavenger efficiency using luminol enhanced chemiluminescence.

21 January 2018

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Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide

21 January 2018

1 reference

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Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system

21 January 2018

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Regional distributions of manganese, iron, copper, and zinc in the brains of 6-hydroxydopamine-induced parkinsonian rats

21 January 2018

1 reference

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Time course of dopaminergic cell death and changes in iron, ferritin and transferrin levels in the rat substantia nigra after 6-hydroxydopamine (6-OHDA) lesioning

21 January 2018

1 reference

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The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

21 January 2018

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Iron misregulation in the brain: a primary cause of neurodegenerative disorders

21 January 2018

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The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

21 January 2018

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10.1080/10715760802270334

21 January 2018

Identifiers

DOI

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15 September 2017

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