(Q39959829)

15 September 2017

GPCR-mediated EGF receptor transactivation regulates TRPV4 action in the vasculature (English)

1 reference

G protein-coupled receptor

15 September 2017

0 references

author

Mahmoud El-Daly

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Peter McIntyre

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Rithwik Ramachandran

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Mahmoud Saifeddine

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Koichiro Mihara

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Nigel W Bunnett

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Christophe Altier

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Morley D Hollenberg

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

18 March 2015

1 reference

British Journal of Pharmacology

15 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

2493-2506

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

13 June 2020

cites work

1 reference

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22 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors

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The Concise Guide to PHARMACOLOGY 2013/14: ion channels

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22 September 2017

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Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways

22 September 2017

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22 September 2017

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TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension

22 September 2017

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Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling.

22 September 2017

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An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

22 September 2017

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Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells

22 September 2017

1 reference

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Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

22 September 2017

1 reference

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Physiology, pharmacology, and therapeutic potential of protease-activated receptors in vascular disease

22 September 2017

1 reference

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Targeting proteinase-activated receptors: therapeutic potential and challenges.

22 September 2017

1 reference

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Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling

22 September 2017

1 reference

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International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress

22 September 2017

1 reference

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G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function

22 September 2017

1 reference

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Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)

22 September 2017

1 reference

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Structure, function and pathophysiology of protease activated receptors.

22 September 2017

1 reference

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Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II

22 September 2017

1 reference

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TRPV channels and vascular function

22 September 2017

1 reference

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Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

22 September 2017

1 reference

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Animal research: reporting in vivo experiments: the ARRIVE guidelines

22 September 2017

1 reference

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Guidelines for reporting experiments involving animals: the ARRIVE guidelines

22 September 2017

1 reference

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Transient receptor potential channels and vascular function

22 September 2017

1 reference

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Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel

22 September 2017

1 reference

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Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

22 September 2017

1 reference

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TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

22 September 2017

1 reference

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Activation of the TRPV4 ion channel is enhanced by phosphorylation.

22 September 2017

1 reference

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TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure

22 September 2017

1 reference

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Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.

22 September 2017

1 reference

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Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling

22 September 2017

1 reference

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Caveolae are required for protease-selective signaling by protease-activated receptor-1.

22 September 2017

1 reference

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TRP channel and cardiovascular disease

22 September 2017

1 reference

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Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2.

22 September 2017

1 reference

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Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.

22 September 2017

1 reference

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The selectivity of protein kinase inhibitors: a further update

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Arterial response to shear stress critically depends on endothelial TRPV4 expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Modulation of tissue factor-factor VIIa signaling by lipid rafts and caveolae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Metabotropic glutamate receptors in the lateral superior olive activate TRP-like channels: age- and experience-dependent regulation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

ADAMs: key components in EGFR signalling and development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

TRP channels as cellular sensors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Abnormal osmotic regulation in trpv4 -/- mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Protein kinase C-mediated Ca2+ entry in HEK 293 cells transiently expressing human TRPV4.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Temperature-modulated diversity of TRPV4 channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

The specificities of protein kinase inhibitors: an update

22 September 2017

1 reference

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A family of calcium-permeable channels in the kidney: distinct roles in renal calcium handling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Thrombin signalling and protease-activated receptors

22 September 2017

1 reference

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International union of pharmacology. XXIII. The angiotensin II receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Bovine endothelial cells in culture produce thromboxane as well as prostacyclin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Serotonin-induced activation of TRPV4-like current in rat intrapulmonary arterial smooth muscle cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Hearing impairment in TRPV4 knockout mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Hyperpolarization of murine small caliber mesenteric arteries by activation of endothelial proteinase-activated receptor 2.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Warm temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Functional TRPV4 channels are expressed in human airway smooth muscle cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Impaired Pressure Sensation in Mice Lacking TRPV4

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Heat-evoked activation of the ion channel, TRPV4.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

Shear stress-induced release of prostaglandin H(2) in arterioles of hypertensive rats.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409902

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FBPH.13072

TxA2 production by human arteries and veins

21 January 2018

1 reference

12 December 2020

Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus

1 reference

12 December 2020

Contraction of diabetic rabbit aorta caused by endothelium-derived PGH2-TxA2

1 reference

12 December 2020

Tyrosine kinase inhibitors and the contractile action of G-protein-linked vascular agonists

1 reference

12 December 2020

Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

12 December 2020

ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II

1 reference

12 December 2020

Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1111/BPH.13072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

25572823

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25572823%20AND%20SRC:MED&resulttype=core&format=json