(Q47852527)

6 February 2018

title

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. (English)

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6 February 2018

author

Emanuel Escher

5

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6 February 2018

Michel Bouvier

7

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6 February 2018

author name string

Brandon Zimmerman

1

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6 February 2018

Alexandre Beautrait

2

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6 February 2018

Benjamin Aguila

3

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6 February 2018

Ricardo Charles

4

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6 February 2018

Audrey Claing

6

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6 February 2018

Stéphane A Laporte

8

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6 February 2018

publication date

24 April 2012

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6 February 2018

published in

Science Signaling

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6 February 2018

volume

5

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6 February 2018

issue

221

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6 February 2018

page(s)

ra33

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6 February 2018

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone

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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

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21 January 2018

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Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

21 January 2018

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Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

21 January 2018

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

21 January 2018

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beta-arrestin-biased agonism at the beta2-adrenergic receptor

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Quantifying ligand bias at seven-transmembrane receptors.

21 January 2018

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Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation

21 January 2018

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Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

21 January 2018

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Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

21 January 2018

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Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

21 January 2018

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Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor

21 January 2018

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Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms

21 January 2018

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Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

21 January 2018

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Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

21 January 2018

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Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure

21 January 2018

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Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.

21 January 2018

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Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling

21 January 2018

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Inferring the lifetime of endosomal protein complexes by fluorescence recovery after photobleaching

21 January 2018

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Study of G protein-coupled receptor/β-arrestin interactions within endosomes using FRAP.

21 January 2018

1 reference

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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

21 January 2018

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The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase

21 January 2018

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Regulation of cell proliferation and growth by angiotensin II.

21 January 2018

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Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.

21 January 2018

1 reference

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Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

21 January 2018

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Studies on angiotensin II and analogs: impact of substitution in position 8 on conformation and activity

21 January 2018

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c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

21 January 2018

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A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002522

Role of ßarrestins in bradykinin B2 receptor-mediated signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002522

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002522

Multiplexing of multicolor bioluminescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002522

c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin- mediated internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002522

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

21 January 2018

1 reference

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Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET).

21 January 2018

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Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration

21 January 2018

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10.1126/SCISIGNAL.2002522

21 January 2018

Identifiers

DOI

1 reference

6 February 2018

PubMed ID

22534132

1 reference

6 February 2018