(Q39960855)

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An early function of the adenoviral E1B 55 kDa protein is required for the nuclear relocalization of the cellular p53 protein in adenovirus-infected normal human cells

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1 reference

Europe PubMed Central

15 September 2017

An early function of the adenoviral E1B 55 kDa protein is required for the nuclear relocalization of the cellular p53 protein in adenovirus-infected normal human cells (English)

1 reference

Europe PubMed Central

15 September 2017

1 reference

based on heuristic

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author name string

F M Cardoso

1

1 reference

Europe PubMed Central

15 September 2017

Sayuri E M Kato

2

1 reference

Europe PubMed Central

15 September 2017

Wenying Huang

3

1 reference

Europe PubMed Central

15 September 2017

S Jane Flint

4

1 reference

Europe PubMed Central

15 September 2017

Ramon A Gonzalez

5

1 reference

Europe PubMed Central

15 September 2017

language of work or name

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publication date

15 July 2008

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Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

378

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Europe PubMed Central

15 September 2017

2

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Europe PubMed Central

15 September 2017

339-346

1 reference

Europe PubMed Central

15 September 2017

Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes

1 reference

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Organization of splicing factors in adenovirus-infected cells reflects changes in gene expression during the early to late phase transition

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

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The interaction of the hnRNP family member E1B-AP5 with p53

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Role of PML and the PML-nuclear body in the control of programmed cell death

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

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E1B55K-deleted adenovirus (ONYX-015) overrides G1/S and G2/M checkpoints and causes mitotic catastrophe and endoreduplication in p53-proficient normal cells

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Bak and Bax function to limit adenovirus replication through apoptosis induction

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Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

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Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

1 reference

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Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.

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Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication

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Replication-selective oncolytic viruses in the treatment of cancer.

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Regulation of p53 activity in nuclear bodies by a specific PML isoform

1 reference

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Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts

1 reference

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Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.

1 reference

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7 January 2021

Regulation of p53 functions: let's meet at the nuclear bodies.

1 reference

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7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

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7 January 2021

p53-dependent cell death/apoptosis is required for a productive adenovirus infection

1 reference

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7 January 2021

Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants

1 reference

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7 January 2021

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

1 reference

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The p53 pathway: positive and negative feedback loops

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7 January 2021

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1 reference

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7 January 2021

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

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7 January 2021

Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: genetic evidence of an adenovirus transformation maintenance function

1 reference

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E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection

1 reference

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Interaction of the adenovirus type 5 E4 Orf3 protein with promyelocytic leukemia protein isoform II is required for ND10 disruption.

1 reference

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Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

1 reference

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Cell-cycle dependent biosynthesis and localization of p53 protein in untransformed human cells

1 reference

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An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

1 reference

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The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

1 reference

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Nuclear matrix localization and SUMO-1 modification of adenovirus type 5 E1b 55K protein are controlled by E4 Orf6 protein.

1 reference

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Experimental infections of humans with wild-type adenoviruses and with replication-competent adenovirus vectors: replication, safety, and transmission

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Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

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Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription

1 reference

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Wild-type p53 protein shows calcium-dependent binding to F-actin

1 reference

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The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function

1 reference

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Viruses - seeking and destroying the tumor program

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Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

1 reference

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Regulation of the p53 tumor suppressor protein

1 reference

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

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PML interaction with p53 and its role in apoptosis and replicative senescence

1 reference

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Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells

1 reference

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

1 reference

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p53 promotes adenoviral replication and increases late viral gene expression

1 reference

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Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein

1 reference

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The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

1 reference

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Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

1 reference

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PML nuclear bodies and apoptosis

1 reference

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Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus

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Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein

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Oncogenic transformation of hamster embryo cells in vitro by adenovirus type 5.

1 reference

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Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export

1 reference

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Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

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Dissection of functional domains in the adenovirus 2 early 1B 55K polypeptide by suppressor-linker insertional mutagenesis

1 reference

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Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

1 reference

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The targeting of the proteasomal regulatory subunit S2 by adenovirus E1A causes inhibition of proteasomal activity and increased p53 expression

1 reference

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E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs

1 reference

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based on heuristic

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The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

1 reference

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p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection

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Monoclonal antibodies specific for simian virus 40 tumor antigens

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Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

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inferred from DOI database lookup

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10.1016/J.VIROL.2008.06.016

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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