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The p53 pathway: positive and negative feedback loops
scientific article (publication date: 18 April 2005)
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title
The p53 pathway: positive and negative feedback loops
(English)
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523
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30 April 2017
author name string
Harris SL
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1
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523
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30 April 2017
Levine AJ
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2
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30 April 2017
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English
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publication date
18 April 2005
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30 April 2017
published in
Oncogene
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30 April 2017
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24
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issue
17
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30 April 2017
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2899-908
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PubMed
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30 April 2017
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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
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Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy
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Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5
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Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function
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The ubiquitin ligase COP1 is a critical negative regulator of p53
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p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors
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Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter
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Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis
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The role of p53 in determining sensitivity to radiotherapy
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The p53MH algorithm and its application in detecting p53-responsive genes
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DNA damage checkpoint control in cells exposed to ionizing radiation
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Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.
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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
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p73 is a simian [correction of human] p53-related protein that can induce apoptosis
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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
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7 January 2021
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p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop
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Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery.
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Targeting the p53-MDM2 interaction to treat cancer
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Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53.
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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
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Crossref
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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
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Crossref
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7 January 2021
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inferred from DOI database lookup
Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study
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Regulation of HDM2 activity by the ribosomal protein L11
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation
1 reference
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Crossref
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inferred from DOI database lookup
Tumor suppression by Ink4a-Arf: progress and puzzles
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Crossref
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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF links the tumour suppressor p53 to Ras
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
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7 January 2021
based on heuristic
inferred from DOI database lookup
Surfing the p53 network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the retinoblastoma protein and the oncoprotein MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin a-CDK phosphorylation regulates MDM2 protein interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 and Promyelocytic Leukemia Antagonize Each Other through Their Direct Interaction with p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1208615
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100296
Dimensions Publication ID
1039884704
0 references
OpenCitations bibliographic resource ID
100296
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100296
PubMed ID
15838523
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100296
ResearchGate publication ID
7897827
0 references
Springer Nature article ID
10.1038/sj.onc.1208615
0 references
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